Results 51 to 60 of about 2,440 (155)

One-month evaluation of safety and immunogenicity of a Vi-DT typhoid conjugate vaccine (Bio-TCV®) in Indonesian subjects 6 months to 45 years: A phase III randomized clinical trial

Vaccine: X
Background: Typhoid fever typically affects children and young adults and is a considerable cause of morbidity and mortality. Vaccination is the most effective preventive strategy to control typhoid fever in the short to medium term.
Bernie Endyarni Medise, I. Gusti Ayu Trisna Windiani, Dominicus Husada, Rini Sekartini, Hartono Gunardi, Angga Wirahmadi, Dwiyanti Puspitasari, Leny Kartina, I. Gusti Agung Ngurah Sugitha Adnyana, I. Gusti Lanang Sidiartha, I. Made Dwi Lingga Utama, I. Ketut Agus Somia, Iris Rengganis, Sukamto Koesnoe, Hindra Irawan Satari, Soedjatmiko Soedjatmiko, Sri Rezeki Hadinegoro, Ismoedijanto Ismoedijanto, Parwati Setiono Basuki, Gatot Soegiarto, Soetjiningsih Soetjiningsih, Rini Mulia Sari, Mita Puspita, Aria Kekalih, Sreshta Mukhi, Vianca Samara Andhary, Novilia Sjafri Bachtiar, Sushant Sahastrabuddhe   +27 more
doaj   +1 more source

Typhoid conjugate vaccines: is a single dose enough for durable protection?

Expert Review of Vaccines
Introduction Typhoid fever is widespread in developing countries. Most typhoid vaccines have gone into some disrepute for their substantial side effects and low efficacy.
Vipin M. Vashishtha, Puneet Kumar
doaj   +1 more source

Phase II multicentre double-blind randomised controlled trial of a Bivalent VaccInation against Salmonella Typhi and Paratyphi A (BiVISTA) using a controlled human infection model of paratyphoid A infection: study protocol

BMJ Open
Introduction Enteric fever, primarily caused by Salmonella enterica Typhi and Salmonella enterica Paratyphi A (SPA), is endemic mainly in South Asia, disproportionately affecting school-age children.
Elizabeth Jones, Xinxue Liu, Andrew J Pollard, Brian Angus, Parvinder Aley, Eleanor Wilson, Hannah Robinson, Amy Flaxman, Prasad S Kulkarni, Nisha Singh, Naina McCann, Young Chan Kim, Margarete Paganotti Vicentine, Oisin Hennigan, Noshi Maria, Claudia I Juarez Molina, Stanislava Koleva, Mohammod K Islam, Nicole Day, Allison MacDonald, Mehreen Adnan, Sophie Vernon, Anirudha Vyankatesh Potey, Abhijeet Dharmadhikari, Sanket Gaidhane, Maheshi Nirmala Ramasamy   +25 more
doaj   +1 more source

A balance between stability and flexibility: Adaptive patterns of self‐regulated learning processes shape game‐based learning

British Journal of Educational Technology, EarlyView.
Abstract To ensure learning efficiency in game‐based learning (GBL), learners must regulate cognitive, affective, metacognitive and motivational (CAMM) processes, collectively known as self‐regulated learning (SRL). SRL is dynamic and non‐linear, characterized by regulatory patterns and CAMM interactions that lead to macro‐level SRL behaviours. In this
Elizabeth B. Cloude, Stefan E. Huber, Jingwei Wei, Bianca Esmanhoto, Muhterem Dindar, Manuel Ninaus, Kristian Kiili   +6 more
wiley   +1 more source

Typhoid Conjugate Vaccines and Enteric Fever Control: Where to Next? [PDF]

Clinical Infectious Diseases, 2020
Abstract After the unprecedented success and acceleration of the global agenda towards typhoid fever control with a strong World Health Organization recommendation and the approval of funding from Gavi, the Vaccine Alliance (Gavi), for the use of a new typhoid conjugate vaccine (TCV), we should turn our minds to the challenges that ...
Steele, AD, Carey, ME, Kumar, S, MacLennan, CA, Ma, L-F, Diaz, Z, Zaidi, AKM   +6 more
openaire   +2 more sources

Simultaneous modification of Thermotoga maritima encapsulin subunits to produce multivalent nanoparticle vaccines for non‐typhoidal Salmonella enterica

The FEBS Journal, EarlyView.
This study investigates the modularity of encapsulin—a protein nanoparticle—by simultaneously inserting up to four distinct Salmonella epitopes within the encapsulin subunit. The encapsulin variants were transiently expressed in plants where they assembled into nanoparticles; however, their accumulation and stability varied depending on the ...
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source

How Fragmented Are Global Policy Debates on Health Data Sharing? Studying Fragmentation Through Discourse Network Analysis

JCMS: Journal of Common Market Studies, Volume 64, Issue 5, Page 1783-1813, September 2026.
Abstract Global policy‐making is often described as taking place in a fragmented and complex institutional landscape. In this article, we revisit the verdict of fragmentation through the lens of discourse network analysis, seeking to understand the extent to which global policy debates can be characterised as fragmented.
Maria Weickardt Soares, Anna Holzscheiter   +1 more
wiley   +1 more source

Typhoid conjugate vaccines for preventing typhoid fever (enteric fever)

Cochrane Database of Systematic Reviews
Typhoid fever is a major cause of enteric disease-related morbidity and mortality. Vaccination reduces disease burden and prevents outbreaks, but policies and programmes should be informed by the most recent evidence as newer vaccines become available.To assess the benefits and harms of typhoid conjugate vaccines (TCVs) compared to no vaccine, placebo,
Gloeck, Natasha R, Leong, Trudy D, Mthethwa, Mashudu, Iwu-Jaja, Chinwe Juliana, Katoto, Patrick DMC, Wiysonge, Charles S, Kredo, Tamara   +6 more
openaire   +2 more sources

Improving Malaria Parasite Gene Flow Inference Under Sparse Spatial Sampling

Molecular Ecology Resources, Volume 26, Issue 6, August 2026.
ABSTRACT Estimating malaria parasite migration is crucial for informing elimination strategies, particularly by identifying regions with higher parasite migration that may serve as transmission sources and intervention targets. Methods that infer spatial variations in gene flow from georeferenced genetic data, including Estimated Effective Migration ...
Yao Li, Bing Guo, Timothy D. O'Connor, Shannon Takala‐Harrison, Kathleen Stewart   +4 more
wiley   +1 more source

Knowledge, Attitudes, and Practices Regarding Typhoid Fever Among University Students in Bangladesh: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Typhoid fever remains a significant public health concern in Bangladesh due to overcrowding, insufficient sanitation, unsafe food and contaminated water exposure, and antimicrobial resistance. The aim of this research is to gather evidence‐based information to guide future public health programs and educational initiatives ...
Most. Nazma Parvin, Md. Muhtamim Hussain Rifat, Sonia Akther Papia   +2 more
wiley   +1 more source