Results 51 to 60 of about 699,460 (251)

THE USE OF TYPHOID VACCINES IN TYPHOID FEVER [PDF]

JAMA: The Journal of the American Medical Association, 1910
The vaccine treatment of typhoid fever has been tested in recent years by a number of clinicians with varying results. Fraenkel1 was the first to call attention to the subject of the treatment of this disease by vaccine therapy. Since the commencement of the year 1909, considerable number of other writers have reported individual experiences of the use
openaire   +1 more source

Target identification for prevention and therapy of "Salmonella" infections [PDF]

, 2014
In this thesis we investigated maintenance requirements of Salmonella during chronic infections, and determined the relevant antigen properties that might facilitate the development of Salmonella vaccines. Overall, we wanted to achieve two goals: a)To
Barat, Somedutta
core   +1 more source

Safety and immunogenicity of the Vi-DT typhoid conjugate vaccine in healthy volunteers in Nepal: an observer-blind, active-controlled, randomised, non-inferiority, phase 3 trial

Lancet. Infectious Diseases (Print), 2021
Summary Background Typhoid fever is an endemic disease in many low-income and middle-income countries. The 2018 WHO position paper recommends that countries should consider typhoid vaccination in high-risk groups and for outbreak control.
Ganesh Kumar Rai, T. Saluja, S. Chaudhary, D. Tamrakar, Piush Kanodia, B. Giri, Rajeev Shrestha, S. Uranw, Deok-ryun Kim, Jae Seung Yang, I. Park, Seung-Eun Kyung, Sridhar Vemula, Jagadeesh Reddy E, Bomi Kim, B. Gupta, Sue-Kyoung Jo, J. Ryu, H. Park, J. Shin, Y. Lee, H. Kim, Jerome H. Kim, Z. Mojares, T. A. Wartel, S. Sahastrabuddhe   +25 more
semanticscholar   +1 more source

A novel Vi-diphtheria toxoid typhoid conjugate vaccine is safe and can induce immunogenicity in healthy Indonesian children 2–11 years: a phase II preliminary report

BMC Pediatrics, 2020
Background Typhoid fever caused by Salmonella enteric serovar Typhi (S. Typhi) is a common cause of morbidity in the world. In 2017, 14.3 million cases of Typhoid and paratyphoid fever occurred globally.
Bernie Endyarni Medise, Soedjatmiko Soedjatmiko, Hartono Gunardi, Rini Sekartini, Hindra Irawan Satari, Sri Rezeki Hadinegoro, Angga Wirahmadi, Mita Puspita, Rini Mulia Sari, Jae Seung Yang, Arijit Sil, Sushant Sahastrabuddhe, Novilia Sjafri Bachtiar   +12 more
doaj   +1 more source

The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26-27 October 2016, Oxford, UK.

Vaccine, 2017
Typhoid fever is estimated to cause between 11.9-26.9 million infections globally each year with 129,000-216,510 deaths. Access to improved water sources have reduced disease incidence in parts of the world but the use of efficacious vaccines is seen as ...
J. Meiring, M. Gibani
semanticscholar   +1 more source

Six-month follow up of a randomized clinical trial-phase I study in Indonesian adults and children: Safety and immunogenicity of Salmonella typhi polysaccharide-diphtheria toxoid (Vi-DT) conjugate vaccine.

PLoS ONE, 2019
IntroductionThere is a high global incidence of typhoid fever, with an annual mortality rate of 200,000 deaths. Typhoid fever also affects younger children, particularly in resource-limited settings in endemic countries.
Bernie Endyarni Medise, Soedjatmiko Soedjatmiko, Iris Rengganis, Hartono Gunardi, Rini Sekartini, Sukamto Koesno, Hindra Irawan Satari, Sri Rezeki Hadinegoro, Jae Seung Yang, Jean-Louis Excler, Sushant Sahastrabuddhe, Mita Puspita, Rini Mulia Sari, Novilia Sjafri Bachtiar   +13 more
doaj   +1 more source

Safety and immunogenicity of Vi-typhoid conjugate vaccine co-administration with routine 9-month vaccination in Burkina Faso: A randomized controlled phase 2 trial

International Journal of Infectious Diseases, 2021
Highlights • This is the first study on the co-administration of typhoid conjugate vaccine (TCV) in West Africa.• Co-administration of TCV with routine vaccines in a typhoid-endemic country was successful.• TCV was safely co-administered at nine months ...
S. Sirima, A. Ouédraogo, N. Barry, M. Siribie, A. Tiono, I. Nebie’, A. Konaté, G. D. Berges, A. Diarra, Moussa Ouedraogo, Edith C. Bougouma, I. Soulama, A. Héma, Shrimati Datta, Yuanyuan Liang, Elizabeth T. Rotrosen, J. Tracy, Leslie P. Jamka, Jennifer J. Oshinsky, M. Pasetti, K. Neuzil, M. Laurens   +21 more
semanticscholar   +1 more source

Efficacy of typhoid conjugate vaccine: final analysis of a 4-year, phase 3, randomised controlled trial in Malawian children

The Lancet
Summary Background Randomised controlled trials of typhoid conjugate vaccines among children in Africa and Asia have shown high short-term efficacy. Data on the durability of protection beyond 2 years are sparse.
P. Patel, Yuanyuan Liang, J. Meiring, Nedson Chasweka, Pratiksha Patel, Theresa Misiri, Felistas Mwakiseghile, R. Wachepa, H. Banda, Florence Shumba, G. Kawalazira, Queen Dube, Nginache Nampota-Nkomba, Osward M. Nyirenda, Tsion Girmay, S. Datta, Leslie P. Jamka, J. Tracy, M. Laurens, R. S. Heyderman, K. Neuzil, Melita A Gordon, Priyanka D Yuanyuan James E Nedson Pratiksha Theresa Felist Patel Liang Meiring Chasweka Patel Misiri Mwakiseg, P. Patel, Yuanyuan Liang, J. Meiring, Nedson Chasweka, Pratiksha Patel, Theresa Misiri, Felistas Mwakiseghile, R. Wachepa, H. Banda, Florence Shumba, G. Kawalazira, Queen Dube, Nginache Nampota-Nkomba, Osward M. Nyirenda, Tsion Girmay, S. Datta, Leslie P. Jamka, J. Tracy, M. Laurens, R. S. Heyderman, K. Neuzil, Melita A Gordon, Chrissy Banda, David Banda, Josephine Chilongo, Amisa Chisale, M. Haward, H. Msuku, J. Ndaferankhande, Chancy Nyirongo, Patricia Phula, James Tamani, Victoria Mapemba, Fleesie A Hubbard, Melissa Myers, Tamar Pair   +58 more
semanticscholar   +1 more source

Vaccines against cholera, typhoid fever and shigellosis for developing countries.

, 2004
Enteric diseases, such as cholera, typhoid fever and shigellosis, still produce a significant burden, especially among the poor in countries where these illnesses are endemic.
Ochiai, RL, Deen, JL, Lee, HJ, Acosta, CJ, von Seidlein, L, Galindo, CM, Carbis, R, Clemens, JD   +7 more
core   +1 more source

Invasive salmonellosis among children admitted to a rural Tanzanian hospital and a comparison with previous studies. [PDF]

, 2010
BACKGROUND: The importance of invasive salmonellosis in African children is well recognized but there is inadequate information on these infections. We conducted a fever surveillance study in a Tanzanian rural hospital to estimate the case fraction of ...
Malahiyo, R, Kim, DR, Deen Jacqueline L., Deen, Jacqueline L, Amos, Ben, Stephen Magesa, Hendriksen, Ilse, Lorenz von Seidlein, Juma Kimera, Hendriksen, ICE, Magesa, S, George Mtove, Magesa Stephen, Mwambuli, A, Kimera, Juma, von Seidlein, L, Hendriksen Ilse, Reyburn Hugh, Clemens, JD, Clemens, John D, Ryun Kim Deok, von Seidlein Lorenz, Kimera Juma, von Seidlein, Lorenz, Ochiai R. Leon, Ben Amos, Ilse Hendriksen, R Leon Ochiai, Mwambuli Abraham, Abraham Mwambuli, Kimera, J, Mwambuli, Abraham, Deok Ryun Kim, Amos, B, Rajabu Mallahiyo, Clemens John D., Ochiai, R Leon, Jacqueline L Deen, Mallahiyo Rajabu, Mtove, GM, Ochiai, RL, Mallahiyo, Rajabu, Deen, JL, John D Clemens, Reyburn, H, Hugh Reyburn, Reyburn, Hugh, Kim, Deok Ryun, Mtove George, Amos Ben, Mtove, George, Magesa, Stephen   +51 more
core   +1 more source