Results 71 to 80 of about 699,460 (251)

Synthetic O‐Polysaccharide Backbone Units for a Single Antigen Vaccine Against Two Major Non‐Typhoidal Salmonella Serovars

Angewandte Chemie International Edition, EarlyView.
A modular strategy was developed to synthesize tri‐, hexa‐, and nona‐saccharides representing repeating units of the conserved O‐polysaccharide backbone of Salmonella. Conjugates of these glycans to bacteriophage Qβ induced strong IgG responses in mice and rabbits. Antibodies elicited recognized native O‐polysaccharides and conferred protection against
Xingling Pan, Changxin Huo, Soham Maity, Herbert Kavunja, Rachel Moszyk, Cameron Talbot, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source

A description of a pre-emptive typhoid Vi capsular polysaccharide vaccination campaign after the 2015 earthquake in Nepal and vaccine effectiveness evaluation

Tropical Medicine and Health
Background A 7.8 R scale earthquake hit Nepal in April 2015 and caused about 9000 deaths along with damage to infrastructure, including the water and sewage system. Bhaktapur was one of the highly affected districts.
Bhim Gopal Dhoubhadel, Ikumi Sawada, Dhruba Shrestha, Yoshifumi Fukuya, Ganendra Bhakta Raya, Eric Ipyn Nébié, Yumiko Hayashi, Rasila Pasakhala, Motoi Suzuki, Konosuke Morimoto, Christopher M. Parry, Koya Ariyoshi   +11 more
doaj   +1 more source

One-month evaluation of safety and immunogenicity of a Vi-DT typhoid conjugate vaccine (Bio-TCV®) in Indonesian subjects 6 months to 45 years: A phase III randomized clinical trial

Vaccine: X
Background: Typhoid fever typically affects children and young adults and is a considerable cause of morbidity and mortality. Vaccination is the most effective preventive strategy to control typhoid fever in the short to medium term.
Bernie Endyarni Medise, I. Gusti Ayu Trisna Windiani, Dominicus Husada, Rini Sekartini, Hartono Gunardi, Angga Wirahmadi, Dwiyanti Puspitasari, Leny Kartina, I. Gusti Agung Ngurah Sugitha Adnyana, I. Gusti Lanang Sidiartha, I. Made Dwi Lingga Utama, I. Ketut Agus Somia, Iris Rengganis, Sukamto Koesnoe, Hindra Irawan Satari, Soedjatmiko Soedjatmiko, Sri Rezeki Hadinegoro, Ismoedijanto Ismoedijanto, Parwati Setiono Basuki, Gatot Soegiarto, Soetjiningsih Soetjiningsih, Rini Mulia Sari, Mita Puspita, Aria Kekalih, Sreshta Mukhi, Vianca Samara Andhary, Novilia Sjafri Bachtiar, Sushant Sahastrabuddhe   +27 more
doaj   +1 more source

Mitigating Health Disparities Through Empathetic Policymaking During Times of Crisis

Public Administration and Development, EarlyView.
ABSTRACT The COVID‐19 pandemic greatly exacerbated the existing disparities and inequities in health and healthcare among historically marginalized populations. Today, these impacts still echo. These persistent structured inequities erode the public's trust in government, lead to failure in public policies, and result in worse health consequences ...
Yali Pang, Brittany Keegan, Robyn D. McDougle   +2 more
wiley   +1 more source

The vaccine data link in Nha Trang, Vietnam: a progress report on the implementation of a database to detect adverse events related to vaccinations.

, 2003
Real, perceived and unknown adverse events secondary to vaccinations are a source of concern for care providers of children. In the USA large linked databases have provided helpful information regarding the safety of vaccines.
Ali, Mohammad, Park, Jin-Kyung, Canh, Do Gia, Clemens, John D, Thiem, Vu Dinh, Tho, Le Huu, Trach, Dang Duc, von Seidlein, Lorenz   +7 more
core   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Differences in perception of dysentery and enteric fever and willingness to receive vaccines among rural residents in China.

, 2006
BACKGROUND: Enteric diseases including dysentery and enteric fever remain significant public health problems in China. While vaccines offer great potential in controlling these diseases, greater understanding of factors influencing acceptance of vaccines
Pack, Robert, Wang, Xuanyi, Nyamette, Andrew, Stanton, Bonita, Pach, Alfred, Gong, Youlong, Chen, Xinguang, von Seidlein, Lorenz, Kaljee, Linda, Clemens, John, Mao, Rong   +10 more
core   +1 more source

Head-to-head comparison of humoral immune responses to Vi capsular polysaccharide and Salmonella Typhi Ty21a typhoid vaccines--a randomized trial. [PDF]

PLoS ONE, 2013
BACKGROUND: The two typhoid vaccines, the parenteral Vi capsular polysaccharide and the oral live whole-cell Salmonella Typhi Ty21a vaccine, provide similar levels of protection in field trials.
Anu Kantele, Sari H Pakkanen, Riitta Karttunen, Jussi M Kantele   +3 more
doaj   +1 more source

Vaccines in Typhoid [PDF]

The Boston Medical and Surgical Journal, 1909
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Watters, W. H., Eaton, C. A.
openaire   +1 more source

Simultaneous modification of Thermotoga maritima encapsulin subunits to produce multivalent nanoparticle vaccines for non‐typhoidal Salmonella enterica

The FEBS Journal, EarlyView.
This study investigates the modularity of encapsulin—a protein nanoparticle—by simultaneously inserting up to four distinct Salmonella epitopes within the encapsulin subunit. The encapsulin variants were transiently expressed in plants where they assembled into nanoparticles; however, their accumulation and stability varied depending on the ...
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source