Results 41 to 50 of about 2,520 (267)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Allionrs Aloe names (Asphodelaceae): nomenclature and typification
Bothalia: African Biodiversity & Conservation, 2009 The taxa belonging to the genus Aloe published in Synopsis methodica stirpium horti regii taurinensis (Allioni 1760) and in Auctarium ad synopsim meihodicam stirpium horti regii taurinensis (Allioni 1773) were examined.
L. Gugliemone +4 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
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Amaranthus palmeri, a second record for Africa and notes on A. sonoriensis nom. nov.
Bothalia: African Biodiversity & Conservation, 2017 Background: Amaranthus is a critical genus from a taxonomic point of view because of its high phenotypic variability, which has led to nomenclatural disorder, misapplication of names, and erroneous species identification.
Duilio Iamonico, Ridha El Mokni
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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GÊNEROS TEXTUAIS, TIPIFICAÇÃO E INTERAÇÃO
Travessias, 2008 In Textual genres, typification and interaction, the north-american teacher and researcher Charles Bazerman emphasizes the social approach for the analysis of textual genres and brings concepts little known by brazilian students and researchers, such as:
Cristina dos Santos Lovato
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Anales del Jardín Botánico de Madrid, 1999 Grimmia arcuatifolia and G. leibergii are recognized as distinct species. Each is known from restricted áreas in northwestern North America. Grimmia alternuata and G.
Jesús Muñoz
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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Nomenclatural types of iberian Irises (Iris and related genera, Iridaceae) [Tipos nomenclaturales de lirios ibéricos (Iris y géneros relacionados, Iridaceaae)] [PDF]
Flora Montiberica, 2012 SUMMARY: Nomenclatural types are reported for seventeen taxa belonging to Iris and six related genera, which are accepted in the forthcoming treatment of Iridaceae for Flora iberica.
Manuel B. CRESPO VILLALBA
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