Results 91 to 100 of about 2,516,098 (344)

HLA Typing in Iraqi Patients with Obesity and Primary Osteoarthritis.

open access: yesمجله كليه طب الكندي, 2013
Background: Osteoarthritis (OA) is a degenerative joint disease. It is one of the major causes of disability in developed and developing countries. Human leukocyte antigen (HLA) as part of immune system has a role in the disease process.Objectives: To ...
Sadiq Abbas Al-Mukhtar   +6 more
doaj  

Phages of Listeria offer novel tools for diagnostics and biocontrol

open access: yesFrontiers in Microbiology, 2014
Historically, bacteriophages infecting their hosts have perhaps been best known and even notorious for being a nuisance in dairy-fermentation processes.
Martin J Loessner, Steven eHagens
doaj   +1 more source

A typed lambda calculus with intersection types

open access: yesTheoretical Computer Science, 2008
AbstractIntersection types are well known to type theorists mainly for two reasons. Firstly, they type all and only the strongly normalizable lambda terms. Secondly, the intersection type operator is a meta-level operator, that is, there is no direct logical counterpart in the Curry–Howard isomorphism sense. In particular, its meta-level nature implies
BONO, Viviana   +2 more
openaire   +5 more sources

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Unsuitability of MALDI-TOF MS to discriminate Acinetobacter baumannii clones under our routine experimental conditions

open access: yesFrontiers in Microbiology, 2015
MALDI-TOF MS (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry) is now in the forefront for routine bacterial species identification methodologies, being its value for clonality assessment controversial.
Clara eSousa   +5 more
doaj   +1 more source

Evolution of strain coverage by the multicomponent meningococcal serogroup B vaccine (4CMenB) in France

open access: yesHuman Vaccines & Immunotherapeutics, 2021
The 4CMenB, a protein-based vaccine, was licensed in Europe in 2013 against invasive meningococcal disease caused by serogroup B and is currently implemented in several countries although according to different national strategies.
Eva Hong   +9 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Conversation Types [PDF]

open access: yesTheoretical Computer Science, 2009
AbstractWe present a type theory for analyzing concurrent multiparty interactions as found in service-oriented computing. Our theory introduces a novel and flexible type structure, able to uniformly describe both the internal and the interface behavior of systems, referred respectively as choreographies and contracts in web-services terminology.
Caires, Luis, Torres Vieira, Hugo
openaire   +4 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Artificially Positive Crossmatches Not Leading to the Refusal of Kidney Donations due to the Usage of Adequate Diagnostic Tools

open access: yesCase Reports in Transplantation, 2013
Allografting patients with human leukocyte antigens (HLA) which are recognized by preformed antibodies constitutes the main cause for hyper-acute or acute rejections.
G. Schlaf   +3 more
doaj   +1 more source

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