Results 301 to 310 of about 14,267,916 (344)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Hippocampal ripples predict motor learning during brief rest breaks in humans. [PDF]

Nat Commun
Sjøgård M, Baxter B, Mylonas D, Thompson M, Kwok K, Driscoll B, Tolosa A, Shi W, Stickgold R, Vangel M, Chu CJ, Manoach DS.   +11 more
europepmc   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Multiple highly resistant clones of MRSA circulating among patients with skin and soft tissue infection, Peshawar, Pakistan 2021-2022. [PDF]

Epidemiol Infect
Ullah A, Frees D, Mansoor M, Jamal SF, Tkadlec J.   +4 more
europepmc   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Molecular epidemiology of <i>Brucella abortus</i> in Shandong, China: high-resolution insights from combined MLVA-16 and core genome SNP analysis. [PDF]

Front Microbiol
Huangfu C, Ma X, Fan J, Han K, Liu T, Kou Z, Li Y.   +6 more
europepmc   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

FEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Tapping into truth: an exploratory cross-sectional analysis of psychomotor symptoms and typing behaviour in an adolescent observational cohort. [PDF]

NPP Digit Psychiatry Neurosci
Braund TA, Bal D, Christensen H, Batterham PJ, Vilus B, Maston K, Larsen ME, Werner-Seidler A, Huckvale K, Whitton AE, Tillman G, O'Dea B.   +11 more
europepmc   +1 more source

Genomics will forever reshape forensic science and criminal justice. [PDF]

Genome Biol
Budowle B, Mittelman K, Mittelman D.
europepmc   +1 more source