Results 51 to 60 of about 14,267,916 (344)

HLA‐HD: An accurate HLA typing algorithm for next‐generation sequencing data

Human Mutation, 2017
The accurate typing of human leukocyte antigen (HLA) alleles is critical for a variety of medical applications, such as genomic studies of multifactorial diseases, including immune system and inflammation‐related disorders, and donor selection in organ ...
S. Kawaguchi, K. Higasa, Masakazu Shimizu, R. Yamada, F. Matsuda   +4 more
semanticscholar   +1 more source

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

Population Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi, Hidaka Kubo, Tokuya Ogawa, Hayate Omura   +3 more
wiley   +1 more source

Molecular Characterisation of Vancomycin-Resistant Enterococcus faecium Isolates Belonging to the Lineage ST117/CT24 Causing Hospital Outbreaks

Frontiers in Microbiology, 2021
Background: Vancomycin-resistant Enterococcus faecium (VREfm) is a successful nosocomial pathogen. The current molecular method recommended in the Netherlands for VREfm typing is based on core genome Multilocus sequence typing (cgMLST), however, the ...
Paola Lisotto, Natacha Couto, Natacha Couto, Sigrid Rosema, Mariëtte Lokate, Xuewei Zhou, Erik Bathoorn, Hermie J. M. Harmsen, Alexander W. Friedrich, John W. A. Rossen, John W. A. Rossen, John W. A. Rossen, Monika A. Chlebowicz-Fliss   +12 more
doaj   +1 more source

Streptococcus suis, an important pig pathogen and emerging zoonotic agent—an update on the worldwide distribution based on serotyping and sequence typing

Emerging Microbes and Infections, 2014
Streptococcus suis is an important pathogen causing economic problems in the pig industry. Moreover, it is a zoonotic agent causing severe infections to people in close contact with infected pigs or pork-derived products.
Guillaume Goyette-Desjardins, Jean-Philippe Auger, Jianguo Xu, M. Segura, M. Gottschalk   +4 more
semanticscholar   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source

Nutritional and Microbial Qualities of Fermented Cereal-Based Porridges Produced in Northern Benin

Journal of Food Quality
Fermentation has been used for centuries to enhance the sensory and nutritional qualities and the antioxidant content of plant-based foods, making them beneficial for health. This study aims to investigate the microbiological and nutritional qualities of
Rachidatou Karimou, Agossou Damien Pacôme Noumavo, Kowiou Aboudou, Bawa Boya, Funkè Faïzatou Assouma, Hafiz Adio Salami, Basile Boni Saka Konmy, Hermance Y. Houngbo, Adolphe Adjanohoun, Lamine Baba-Moussa, Haziz Sina   +10 more
doaj   +1 more source

A Falsification View of Success Typing

, 2015
Dynamic languages are praised for their flexibility and expressiveness, but static analysis often yields many false positives and verification is cumbersome for lack of structure.
Jakob, Robert, Thiemann, Peter
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Phylogenetic analysis of the enigmatic Kalash population in Pakistan

Scientific Reports
The genetic origin of the Kalash, an isolated community in northern Pakistan, have long been a subject of debate. This study aimed at investigating the genetic diversity and ancestral composition of Kalash people using an advanced set of genetic data ...
Imran Shahid, Faqeeha Javed, Abida Shehzadi, Jaweria Munsif, Ahmad Ali Shahid, Muhammad Shafique   +5 more
doaj   +1 more source

Group B Streptococcus CRISPR1 Typing of Maternal, Fetal, and Neonatal Infectious Disease Isolates Highlights the Importance of CC1 in In Utero Fetal Death

Microbiology Spectrum, 2023
We performed a descriptive analysis of group B Streptococcus (GBS) isolates responsible for maternal and fetal infectious diseases from 2004 to 2020 at the University Hospital of Tours, France.
Brice Le Gallou, Adeline Pastuszka, Coralie Lemaire, Laurent Mereghetti, Philippe Lanotte   +4 more
doaj   +1 more source