Results 61 to 70 of about 14,267,916 (344)

Touch Typing Tutor for visually impaired children and young people [PDF]

open access: yes, 2000
Touch Typing Tutor is a software programme which was designed to assist teaching touch typing skills to visually impaired children. It was first designed and written in the 1990s by Graeme Douglas and Alan Gamble and then updated in 2000 and is now ...
Douglas, Graeme, Gamble, Alan
core  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

No-err typing aids [PDF]

open access: yes, 1972
Device for aligning paper in typewriter to correct one letter or line of type is discussed.
Dubois, R. D., Pinson, G. T.
core   +1 more source

Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia [PDF]

open access: yes, 2019
Introduction Chromosomal abnormalities are frequent events in hematological malignancies. The degree of HLA compatibility between donor and recipient in hematopoietic stem cell transplantation is critical.
Breman, Amy M.   +10 more
core   +1 more source

Diagnosis of toxoplasmosis and typing of Toxoplasma gondii

open access: yesParasites & Vectors, 2015
Toxoplasmosis, caused by the obligate intracellular protozoan Toxoplasma gondii, is an important zoonosis with medical and veterinary importance worldwide.
Quan Liu   +3 more
semanticscholar   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Call-by-value non-determinism in a linear logic type discipline [PDF]

open access: yes, 2013
We consider the call-by-value lambda-calculus extended with a may-convergent non-deterministic choice and a must-convergent parallel composition. Inspired by recent works on the relational semantics of linear logic and non-idempotent intersection types ...
A. Bernadet   +14 more
core   +4 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

CRISPR Typing Increases the Discriminatory Power of Streptococcus agalactiae Typing Methods

open access: yesFrontiers in Microbiology, 2021
We explored the relevance of a Clustered regularly interspaced short palindromic repeats (CRISPR)-based genotyping tool for Streptococcus agalactiae typing and we compared this method to current molecular methods [multi locus sequence typing (MLST) and ...
Clémence Beauruelle   +15 more
doaj   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

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