Results 161 to 170 of about 674,878 (317)

Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate. [PDF]

open access: yesElife
Borar P   +8 more
europepmc   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum   +28 more
wiley   +1 more source

RNF213-Dependent EGFR and HER2 Activation Regulates Specific Downstream Signaling Pathways in Human Cancer Cells. [PDF]

open access: yesGenes Cells
Fouad IM   +9 more
europepmc   +1 more source

Multienzyme (3‐in‐1)‐Mimicking a Single Nucleobase‐Derived Bionanozyme for Versatile Environmental and Biomedical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports the development of bioinspired 2D crystalline Bionanozyme derived from a single nucleobase. It effectively mimics multienzyme activity to detect and remove phenolic pollutants, identify disease biomarkers with high sensitivity, and protect cells from oxidative stress.
Subrat Vishwakarma   +8 more
wiley   +1 more source

Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim   +7 more
wiley   +1 more source

FURTHER ANALYSIS OF THE RÔLE OF ASCORBIC ACID IN PHENYLALANINE AND TYROSINE METABOLISM

open access: hybrid, 1941
Robert Ridgely Sealock   +2 more
openalex   +1 more source

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