Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate. [PDF]
Borar P+8 more
europepmc +1 more source
Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum+28 more
wiley +1 more source
RNF213-Dependent EGFR and HER2 Activation Regulates Specific Downstream Signaling Pathways in Human Cancer Cells. [PDF]
Fouad IM+9 more
europepmc +1 more source
THE SOURCE OF LYSINE, TYROSINE, AND PHOSPHORUS FOR CASEIN SYNTHESIS
J. M. Barry
openalex +1 more source
The influence of
H. A. Painter, S. S. Zilva
openalex +1 more source
This study reports the development of bioinspired 2D crystalline Bionanozyme derived from a single nucleobase. It effectively mimics multienzyme activity to detect and remove phenolic pollutants, identify disease biomarkers with high sensitivity, and protect cells from oxidative stress.
Subrat Vishwakarma+8 more
wiley +1 more source
THE PARTIAL REPLACEMENT OF DIETARY PHENYLALANINE BY TYROSINE FOR PURPOSES OF GROWTH
Madelyn Womack, William C. Rose
openalex +1 more source
Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim+7 more
wiley +1 more source
Metabolomic profiling uncovers diagnostic biomarkers and dysregulated pathways in Parkinson's disease. [PDF]
Chen H+6 more
europepmc +1 more source
FURTHER ANALYSIS OF THE RÔLE OF ASCORBIC ACID IN PHENYLALANINE AND TYROSINE METABOLISM
Robert Ridgely Sealock+2 more
openalex +1 more source