Results 161 to 170 of about 519,424 (350)

Dok‐3 sequesters Grb2 and inhibits the Ras‐Erk pathway downstream of protein‐tyrosine kinases [PDF]

, 2006
Miyuki Honma, Osamu Higuchi, Masaki Shirakata, Tomoharu Yasuda, Hiroshi Shibuyà, Shun‐ichiro Iemura, Tohru Natsume, Yuji Yamanashi   +7 more
openalex   +1 more source

Oral spleen tyrosine kinase/Janus Kinase inhibitor gusacitinib for the treatment of chronic hand eczema: Results of a randomized phase 2 study [PDF]

, 2023
Pablo A. Jimenez, Howard Sofen, Robert Bissonnette, Mark Lee, Joseph F. Fowler, David J. Zammit, Yusong Chen, Niranjan Rao, Louis Denis, Sandeep Kumar Gupta   +9 more
openalex   +1 more source

Tyrosine Kinase Inhibitor–associated Fibrothorax [PDF]

American Journal of Respiratory and Critical Care Medicine, 2019
Andres M, Adrianza, Carlos A, Jimenez, Grecia L, Aldana, Leonardo, Pozo, Jorge E, Cortes, Ala Eddin S, Sagar   +5 more
openaire   +2 more sources

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Severe toxicity of skin rash, fever and diarrhea associated with imatinib: case report and review of skin toxicities associated with tyrosine kinase inhibitors

Drug Design, Development and Therapy, 2008
Xuan Huang1, Samir Patel2, Nasir Ahmed2, Karen Seiter2, Delong Liu21Department of Medicine, Richmond University Medical Center, New York, NY, USA; 2Division of Oncology and Hematology, New York Medical College and Westchester Medical Center, New York, NY,
Delong Liu, Karen Seiter, Nasir Ahmed, Samir Patel, Xuan Huang   +4 more
doaj  

Data from Targeting c-Myc to Overcome Acquired Resistance of EGFR Mutant NSCLC Cells to the Third-Generation EGFR Tyrosine Kinase Inhibitor, Osimertinib

, 2023
Lei Zhu, Zhen Chen, Hongjing Zang, Songqing Fan, Jiajia Gu, Guojing Zhang, Kevin D.-Y. Sun, Qiming Wang, Yong He, Taofeek K. Owonikoko, Suresh S. Ramalingam, Shi‐Yong Sun   +11 more
openalex   +1 more source

Anti-Angiogenic Therapy: Albumin-Binding Proteins Could Mediate Mechanisms Underlying the Accumulation of Small Molecule Receptor Tyrosine Kinase Inhibitors in Normal Tissues with Potential Harmful Effects on Health [PDF]

, 2021
Nicolae Ghinea
openalex   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes

, 2019
Anna L Coleman-Hulbert, Erik Johnson, Christine A. Sedore, Stephen A. Banse, Max Guo, Monica Driscoll, Gordon J. Lithgow, Patrick C. Phillips   +7 more
openalex   +2 more sources

Supplementary Figures 1-4 from Stromal Niche Cells Protect Early Leukemic FLT3-ITD⁺ Progenitor Cells against First-Generation FLT3 Tyrosine Kinase Inhibitors

, 2023
Amanda Parmar, Stefanie Marz, Sally Rushton, Christina Holzwarth, Katarina Lind, Sabine Käyser, Konstanze Döhner, Christian Peschel, Robert A.J. Oostendorp, Katharina S. Götze   +9 more
openalex   +1 more source