Results 251 to 260 of about 1,885,895 (335)

Second Primary Malignancies in Patients With B-Cell Lymphomas Treated With Bruton's Tyrosine Kinase Inhibitors: A Systematic Review and Meta-Analysis. [PDF]

Eur J Haematol
Ma C, Lu Y, Li J, Liu W, Liu J.
europepmc   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +2 more sources

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Advances in understanding the mechanisms underlying acquired resistance to third-generation tyrosine kinase inhibitors in non-small cell lung cancer. [PDF]

Front Cell Dev Biol
A-Lai GH, Li L, Ma G, Zhao YS, Yao P, Lin YD.   +5 more
europepmc   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Early-Phase Activation of Epithelial-Mesenchymal Transition in Lung Cancer Cells Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. [PDF]

Int J Mol Sci
Belloni A, Tamberi L, Graciotti L, Spadoni T, Matacchione G, Giordani C, Giuliani A, Chiadini E, Capelli L, Donno E, Sbrighi C, Zanoni M, Ulivi P, Rippo MR, Crinò L, Canale M, Bronte G.   +16 more
europepmc   +1 more source

Age-stratified adverse-event reporting signals of seven ALK/ROS1 tyrosine kinase inhibitors in FAERS: a disproportionality and time to onset study. [PDF]

Front Pharmacol
Liu Y, Yu Y, Yu Y, Huang X, Zhong H.
europepmc   +1 more source

Marine‐Derived Type I Collagen From Scyliorhinus canicula: Extraction, Characterization, and Biomedical Applications

Journal of Applied Polymer Science, EarlyView.
Marine‐derived type I collagen is extracted from Scyliorhinus canicula skin and characterized by physicochemical and morphological analyses. The collagen exhibits excellent biocompatibility, promotes wound healing, reduces inflammatory mediators, and inhibits melanogenesis.
Marwa Rejeb, Aida Lahmar, Arem Selmi, Tahsine Kosksi, Nawres Debbabi, Ghania Hamdi‐Degobert, Leila Chekir‐Ghedira   +6 more
wiley   +1 more source

Cost of managing brain metastases in patients with ALK+ advanced NSCLC with first-line tyrosine kinase inhibitors in the UK. [PDF]

Lung Cancer Manag
Le H, Ladino D, Lowry C, Rifi N, Baijal S.   +4 more
europepmc   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source