Results 301 to 310 of about 857,410 (384)

Salicylates Inhibit T Cell Adhesion on Endothelium Under Nonstatic Conditions: Induction of L-Selectin Shedding by a Tyrosine Kinase-Dependent Mechanism

, 2001
Roberto Gerli, Paolo Gresele, Onelia Bistoni, Cristina Paolucci, Luisa Lanfrancone, Stefano Fiorucci, Christopher Muscat, V. Costantini   +7 more
openalex   +1 more source

π‐PhenoDrug: A Comprehensive Deep Learning‐Based Pipeline for Phenotypic Drug Screening in High‐Content Analysis

Advanced Intelligent Systems, EarlyView.
This study develops a deep learning‐based pipeline named π‐PhenoDrug for cell phenotype‐driven drug activity screening. π‐PhenoDrug integrates cell segmentation, morphological profile construction, and phenotype analysis modules, and it can assess drug effects on living cells in both supervised and unsupervised modes.
Xiao Li, Qinxue Ouyang, Mingfei Han, Xiaoqing Liu, Fuchu He, Yunping Zhu, Ling Leng, Jie Ma   +7 more
wiley   +1 more source

Comparing novel treatments in chronic spontaneous urticaria: A critical appraisal of Bruton's tyrosine kinase inhibitors versus anti-cytokine biologics in clinical trials. [PDF]

Clin Transl Allergy
Diamanti A, Tontini C, Bulfone-Paus S.
europepmc   +1 more source

Mixed Autoimmune Hemolytic Anemia: A Systematic Review of Epidemiology, Clinical Characteristics, Therapies, and Outcomes

American Journal of Hematology, EarlyView.
Mixed autoimmune hemolytic anemia (AIHA) is a rare condition characterized by the presence of both warm and cold autoantibodies, often leading to severe, treatment‐resistant hemolysis. In this systematic review of 81 patients across 35 studies, the median age was 45 years with a notable female predominance.
Jeremy W. Jacobs, Sheharyar Raza, Landon M. Clark, Laura D. Stephens, Elizabeth S. Allen, Jennifer S. Woo, Rachel Lane Walden, Cristina A. Figueroa Villalba, Christopher A. Tormey, Caroline G. Stanek, Brian D. Adkins, Evan M. Bloch, Garrett S. Booth   +12 more
wiley   +1 more source

Do germline genetic variants affect the efficacy of epidermal growth factor receptor tyrosine kinase inhibitors? [PDF]

Transl Cancer Res
Masago K, Fujita S, Sasaki E, Horio Y.
europepmc   +1 more source

Tyrosine kinase inhibitors in patients with neuroendocrine neoplasms: a systematic literature review. [PDF]

Ther Adv Med Oncol
Taboada RG, Cavalher FP, Rego JF, Riechelmann RP.   +3 more
europepmc   +1 more source

Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKI) for optimized outcome in patients with metastatic renal cell carcinoma. The TKI-TDM Trial. Study protocol. [PDF]

Acta Oncol
Henriksen JN, Andersen CU, Donskov F, Hoffmann-Lücke E, Greibe E, Fristrup N.   +5 more
europepmc   +1 more source

Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore, Gianmichele Migaleddu, Pei‐Chien Tsai, Antonella Fogli, Maria Adelaide Caligo, Gabriele Siciliano, Mirco Cosottini, Yi‐Chung Lee, Yi‐Chu Liao, Michelangelo Mancuso, Roberto Ceravolo, Daniela Frosini   +11 more
wiley   +1 more source

First-line treatment of hepatocellular carcinoma: a propensity-matched analysis of tyrosine kinase inhibitors combined with TACE, with or without PD-1 inhibitors. [PDF]

Front Pharmacol
Shen Y, Xu Y, Teng Y, Ding X, Chen J.
europepmc   +1 more source