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Protein tyrosine phosphorylation in streptomycetes

FEMS Microbiology Letters, 1994
Using phosphotyrosine-specific antibodies, we demonstrate that in several Streptomyces spp. a variety of proteins are phosphorylated on tyrosine residues. Tyrosine phosphorylation was found in a number of Streptomyces species including Streptomyces lividans, Streptomyces hygroscopicus and Streptomyces lavendulae. Each species exhibited a unique pattern
Waters, Barbara   +3 more
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Tyrosine phosphorylation in human lymphomas

The Histochemical Journal, 2003
In a previous study, we showed that the high level of protein tyrosine phosphorylation present in lymphomas containing an anaplastic lymphoma kinase (ALK) can be demonstrated in routinely processed paraffin tissue sections using immunolabelling techniques.
Haralambieva, E   +18 more
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Role of Tyrosine Phosphorylation in PTP–PEST

The Journal of Physical Chemistry B, 2023
We study the influence of tyrosine phosphorylation on PTP-PEST, a cytosolic protein tyrosine phosphatase. Utilizing a combination of experimental data and computational modeling, specific tyrosine sites, notably Y64 and Y88, are identified for potential phosphorylation.
T S Sreevidya   +4 more
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Tyrosine phosphorylation

1996
Abstract 1. A role for tyrosine phosphorylation in signal transduction One of the central questions in cell biology is how do cells communicate with each other and their environment, and how does an individual cell regulate itself? Characterization of the proteins that regulate extracellular and intracellular signal transduction has lead
Edwin A Clark, Joans. Brugge
openaire   +1 more source

Tyrosine phosphorylation in human neutrophil

Biochemical and Biophysical Research Communications, 1989
Protein tyrosine phosphorylation in human neutrophils was examined by immunoblotting with antibodies specific for phosphotyrosine. The addition of the human hormone granulocyte-macrophage colony stimulating factor to human neutrophils caused an increase in the tyrosine phosphorylation levels of several proteins.
J, Gomez-Cambronero   +6 more
openaire   +2 more sources

Tyrosine phosphorylation in plant bending

Nature, 2000
Puckering in a ticklish plant is controlled by dephosphorylation of its actin. The phosphorylation of the amino acid tyrosine in animal proteins acts as an on–off switch in numerous pathways that regulate growth, differentiation and oncogenesis1,2. In the unicellular slime mould Dictyostelium , tyrosine-phosphorylation of actin controls cell-shape ...
K, Kameyama   +5 more
openaire   +2 more sources

Tyrosine phosphorylation in Escherichia coli

Journal of Molecular Biology, 1998
The phosphorylation on tyrosine of a protein in Escherichia coli both in vivo and in vitro was revealed by recognition by anti-phosphotyrosine antibodies, labelling with [gamma-32P]ATP, and phosphoamino acid analysis. This protein, which we name TypA, is the product of the o591 reading frame as revealed by N-terminal sequencing and antibody cross ...
Freestone, P   +4 more
openaire   +3 more sources

Conformational Clusters of Phosphorylated Tyrosine

Journal of the American Chemical Society, 2017
Tyrosine phosphorylation plays an important role in many cellular and intercellular processes including signal transduction, subcellular localization, and regulation of enzymatic activity. In 1999, Blom et al., using the limited number of protein data bank (PDB) structures available at that time, reported that the side chain structures of ...
Maha Abdelrasoul   +6 more
openaire   +2 more sources

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