Results 101 to 110 of about 4,798 (243)

Hormonally and chemically defined expansion conditions for organoids of biliary tree Stem Cells

Bioactive Materials
Wholly defined ex vivo expansion conditions for biliary tree stem cell (BTSC) organoids were established, consisting of a defined proliferative medium (DPM) used in combination with soft hyaluronan hydrogels.
Wencheng Zhang, Yangyang Cui, Mengqi Lu, Mingyang Xu, Yuting Li, Haimeng Song, Yi Luo, Jinjia Song, Yong Yang, Xicheng Wang, Lijun Liao, Yunfang Wang, Lola Reid, Zhiying He   +13 more
doaj   +1 more source

Fungal infections in liver transplant recipients [PDF]

, 1985
Sixty-two adults who underwent orthotopic liver transplantations between February 1981 and June 1983 were followed for a mean of 170 days after the operation. Twenty-six patients developed 30 episodes of significant fungal infection.
Dummer, JS, Ho, M, Iwatsuki, S, Shaw, B, Starzl, TE, Van Thiel, DH, Wajszczuk, CP   +6 more
core   +1 more source

Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease

Cells
Hepatocyte transplantation (HTx) combined with ex vivo gene therapy has garnered significant interest due to its potential for treating many inherited metabolic liver diseases.
Justin Gibson, Abishek Dhungana, Menam Pokhrel, Benjamin Arthur, Pramita Suresh, Olumide Adebayo, Renee N. Cottle   +6 more
doaj   +1 more source

Comment on Dijkstra et al. A False-Negative Newborn Screen for Tyrosinemia Type 1—Need for Re-Evaluation of Newborn Screening with Succinylacetone. Int. J. Neonatal Screen. 2023, 9, 66

International Journal of Neonatal Screening
The assessment of newborn screening (NBS) algorithms’ performance to ensure quality improvements is a continuous process: false-positive referrals can enable optimisations in the shorter term, but false-negative referrals are often only discovered many ...
Marelle J. Bouva, Rose E. Maase, Ruurd M. van Elburg   +2 more
doaj   +1 more source

Evaluation of Neonatal Screening Programs for Tyrosinemia Type 1 Worldwide

International Journal of Neonatal Screening
In The Netherlands, newborn screening (NBS) for tyrosinemia type 1 (TT1) uses dried blood spot (DBS) succinylacetone (SUAC) as a biomarker. However, high false-positive (FP) rates and a false-negative (FN) case show that the Dutch TT1 NBS protocol is ...
Allysa M. Kuypers, Marelle J. Bouva, J. Gerard Loeber, Anita Boelen, Eugenie Dekkers, Konstantinos Petritis, C. Austin Pickens, The ISNS Representatives, Francjan J. van Spronsen, M. Rebecca Heiner-Fokkema   +9 more
doaj   +1 more source

A Single Mutation of the Fumarylacetoacetate Hydrolase Gene in French Canadians with Hereditary Tyrosinemia Type I [PDF]

, 1994
Markus Grompe, Maryse St.-Louis, Sylvie I. Demers, Muhsen Al-Dhalimy, B. Leclerc, Robert M. Tanguay   +5 more
openalex   +1 more source

"A Case Report of a Female Child with Tyrosinemia Type I in Southern Philippines During the Covid-19 Pandemic" [PDF]

, 2023
G Beley
openalex   +1 more source

Hereditary tyrosinemia type Ⅰ: newborn screening, diagnosis and treatment. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban, 2021
Tang Y, Kong Y.
europepmc   +1 more source

141 PATHOGENESIS OF EREDITARY TYROSINEMIA TYPE I: METABOLID DISORDERS IN CULTURED HEPATOCYTES FROM TRANSPLANATION PATIENTS [PDF]

, 1991
Etienne Agsteribbe, Henk van Faassen, Marijke Hartog, M. J. H. Slooff, G W Sandker, Folkert Kuipers, Gerrit Smit, C. M. A. Bijleveld, H. S. A. Heijmans   +8 more
openalex   +1 more source

A Compensatory U1snRNA Partially Rescues FAH Splicing and Protein Expression in a Splicing-Defective Mouse Model of Tyrosinemia Type I. [PDF]

Int J Mol Sci, 2020
Balestra D, Scalet D, Ferrarese M, Lombardi S, Ziliotto N, C Croes C, Petersen N, Bosma P, Riccardi F, Pagani F, Pinotti M, van de Graaf SFJ.   +11 more
europepmc   +1 more source