Results 121 to 130 of about 4,877,471 (257)

New U-Pb geochronology for the Central Atlantic Magmatic Province, critical reevaluation of high-precision ages and their impact on the end-Triassic extinction event. [PDF]

Sci Rep, 2023
Oliveira AL, Schmitz MD, Wall CJ, Crowley JL, Macêdo Filho AA, Hollanda MHBM.   +5 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Pace of passive margin tectonism revealed by U-Pb dating of fracture-filling calcite. [PDF]

Nat Commun, 2022
Amidon WH, Kylander-Clark ARC, Barr MN, Graf SFI, West DP.   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

How Robust is the Cassiterite U-Pb Geochronometer? [PDF]

Goldschmidt Abstracts, 2020
Leonid Neymark, Richard Moscati, Anatoly Larin, John Slack   +3 more
openaire   +1 more source

Zircon U-Pb chronology on plutonic rocks from northeastern Cambodia. [PDF]

Heliyon, 2021
Kasahara N, Niki S, Uchida E, Yarimizu K, Cheng R, Hirata T.   +5 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The effect of low-temperature annealing on discordance of U-Pb zircon ages. [PDF]

Sci Rep, 2021
Herrmann M, Söderlund U, Scherstén A, Næraa T, Holm-Alwmark S, Alwmark C.   +5 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

U-Pb dating and geochemical dataset of fracture-filling calcite veins from the Bóixols-Sant Corneli anticline (Southern Pyrenees). [PDF]

Data Brief, 2022
Muñoz-López D, Cruset D, Vergés J, Cantarero I, Benedicto A, Baqués V, Mangenot X, Albert R, Gerdes A, Beranoaguirre A, Travé A.   +10 more
europepmc   +1 more source