Results 131 to 140 of about 166,341 (292)

U-Pb dating of zircon in Mesosiderite Asuka-882023 [PDF]

open access: yes, 2016
第4回極域科学シンポジウム個別セッション:[OA] 南極隕石11月14日(木)~15日(金) 国立国語研究所 2階ラウンジ ...

core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

U-Pb dating for zircons from granitic rocks in southwestern Cambodia. [PDF]

open access: yesHeliyon, 2023
Uchida E   +6 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

U-Pb dating of niobium minerals from the pyrochlore group (Ilmeny-Vishnevogorsky carbonatite-miaskite complex, South Urals)

open access: yesЛитосфера, 2020
The article covers the U-Pb dating of minerals belonging to the pyrochlore group from the rare-metal ore deposits of Ilmeny-Vishnevogorsky carbonatite-miaskite complex (South Urals). Individual pyrochlore crystals were dated through a new technique of in-
I. L. Nedosekova   +5 more
doaj  

P-T-t path for the Archean Pikwitonei Granulite Domain and Cross Lake Subprovince, Manitoba, Canada [PDF]

open access: yes
The rationale was outlined for constructing pressure-temperature-time (P-T-t) paths by using U-Pb dating of garnet produced in thermobarometrically sensitive reactions. In an example from the Pikwitonei granulites of the Northwestern Superior Province of
Bohlen, S. R., Hanson, G. N., Mezger, K.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

High Spatial Resolution U-Pb Dating of Low-Uranium Calcite Using LA-MC-ICP-MS

open access: yesYankuang ceshi
The combination of carbonate minerals with the U-Pb isotope dating system provides direct temporal constraints for geoscientific applications. LA-MC-ICP-MS with its high sensitivity and accuracy, has been successfully applied to the high spatial ...
Chenxi ZHANG   +8 more
doaj   +1 more source

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