Results 181 to 190 of about 4,877,471 (257)

U-Pb geochronology of carbonate-hosted Pb-Zn ores reveals plate-tectonic evolution of eastern Asia during the early Paleozoic. [PDF]

Sci Rep
Li B, Zhang WD, Zhao JX, Liu P, Feng JP, Feng YX, Xiao Y.   +6 more
europepmc   +1 more source

U-Pb zircon geochronology and phase equilibria modelling of HP-LT rocks in the Ossa-Morena Zone, Portugal. [PDF]

Int J Earth Sci, 2020
Akker IV, Tajčmanová L, Marques FO, Burg JP.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

High-precision U-Pb zircon dating identifies a major magmatic event on the Moon at 4.338 Ga. [PDF]

Sci Adv
Barboni M, Szymanowski D, Schoene B, Dauphas N, Zhang ZJ, Chen X, McKeegan KD.   +6 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Simultaneous determination of zircon U-Pb age and titanium concentration using LA-ICP-MS: Analysis data and crystallization temperature. [PDF]

Data Brief, 2020
Yuguchi T, Ishibashi K, Sakata S, Yokoyama T, Itoh D, Ogita Y, Yagi K, Ohno T.   +7 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Geochemical characteristics and detrital zircon U-Pb ages of the Yimin Formation, Kelulun Depression, Hailar Basin and constraints on uranium mineralization. [PDF]

PLoS One
Meng F, Nie F, Xia F, Yan Z, Sun D, Zhou W, Zhang X, Wang Q.   +7 more
europepmc   +1 more source

Long-term repeatability and interlaboratory reproducibility of high-precision ID-TIMS U-Pb geochronology.

J Anal At Spectrom, 2021
Schaltegger U, Schaltegger U, Ovtcharova M, Gaynor SP, Schoene B, Wotzlaw JF, Davies JFHL, Farina F, Greber ND, Szymanowski D, Chelle-Michou C.   +10 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source