Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Correlation Between U/Th and Pb/Os Abundance Ratios and its Application in Nuclear Cosmochronology
The abundance ratios of radioactive elements U/Th and stable elements Pb/Os from the r -process are found to have a strong correlation. This correlation is quite robust with respect to astrophysical conditions.
Y. Y. Huang +3 more
doaj +1 more source
Late Miocene magmatic activity in the Attic-Cycladic Belt of the Aegean (Lavrion, SE Attica, Greece): implications for the geodynamic evolution and timing of ore deposition [PDF]
Numerous post-metamorphic Miocene granitoids occur in the area of Lavrion, SE Attica, at the western end of the Attic-Cycladic Belt of the Aegean. U-Pb ion microprobe-dating (SHRIMP) of zircon from a granitoid sill in the hanging-wall of a regional ...
LIATI, ANTHI +2 more
core
Evidence of Multiple r-Process Sites in the Early Galaxy: New Observations of CS 22892-052
First results are reported of a new abundance study of neutron-capture elements in the ultra-metal-poor (UMP; [Fe/H] = -3.1) halo field giant star CS 22892-052.
Christopher Sneden +7 more
core +1 more source
Geochemical and geochronological constraints on the geologic evolution of the western Sonobari Complex, northwestern Mexico [PDF]
In the southern Sierra Sonobari, NW Mexico, U-Pb and 40Ar/39Ar geochronology studies allowed to define the provenance and maximum depositional age of the Francisco Gneiss basement of the Sonobari terrane, and to establish the age of some magmatic events ...
Gómez-Juárez, O.S. +5 more
core +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
U-Pb isotopic characteristics of lunar meteorites Yamato-793274 and Yamato-86032 [PDF]
U-Pb data from lunar meteorites Yamato (Y)-86032 and Y-793274 confirm that they are of lunar origin, but also indicate that they are not from the same source region on the Moon and experienced different events while residing as lunar regolith.
Premo,Wayne R., Tatsumoto,Mitsunobu
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Turning Trash Into Treasure: Extracting Meaning From Discordant Data via a Dedicated Application
Zircon U–Pb geochronology is a vital tool for dating geological events, but interpreting discordant zircon ages—often the result of Pb loss due to fluid‐rock interactions—remains challenging.
Lucy M. Mathieson +2 more
doaj +1 more source

