Results 131 to 140 of about 189,480 (262)

U/Pb and Pb/Pb zircon ages for arc-related intrusions of the Bolu Massif (W Pontides, NW Turkey): evidence for Late Precambrian (Cadomian) age

, 2005
We present new U/Pb and Pb/Pb radiometric age data from two tectono-stratigraphic units of the regionally extensive Bolu Massif, in the W Pontides (Istanbul Fragment), N Turkey.
Mundil, Roland, USTAÖMER, Petek Ayda, Renne, Paul R.   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

U-Pb dating of calcite-aragonite layers in speleotherms from hominin sites in South Africa by MC-ICP-MS

, 2010
Speleothems are found in association with hominin fossil-bearing cave deposits in South Africa and can be used to provide valuable chronological constraints.
Kramers, J., Pettke, Thomas, Kramers, Jan D., Partridge, T., Pickering, Robyn, Kodolanyi, J., Pickering, R., Partridge, Tim   +7 more
core   +1 more source

Electron microprobe dating of lunar zirconolite

Journal of Analytical Science and Technology
Zirconolite is an accessary mineral occurred in the lunar basaltic and granitic rocks and contains relatively high contents of U, Th, and Pb, which is attractive for age dating.
Changkun Park, Hwayoung Kim
doaj   +1 more source

U-Pb dating of niobium minerals from the pyrochlore group (Ilmeny-Vishnevogorsky carbonatite-miaskite complex, South Urals)

Литосфера, 2020
The article covers the U-Pb dating of minerals belonging to the pyrochlore group from the rare-metal ore deposits of Ilmeny-Vishnevogorsky carbonatite-miaskite complex (South Urals). Individual pyrochlore crystals were dated through a new technique of in-
I. L. Nedosekova, V. A. Koroteev, B. V. Belyatsky, V. V. Sharygin, Е. N. Lepechinа, S. V. Pribavkin   +5 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A database of detrital zircon U–Pb ages and Hf isotope of Precambrian strata in South China

Geoscience Data Journal
Detrital zircon U–Pb chronology database of Precambrian deposits provides a context for the interpretation of the origin and evolution of ancient crust.
Chengzhang Luo, Liang Qi, Tianle Xia
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Rhenium-osmium geochronology and geochemistry of ancient lacustrine sedimentary and petroleum systems [PDF]

, 2013
The Re-Os geochronometer is a valuable tool able to provide precise depositional ages of marine organic-rich sedimentary rocks as well as the generation age of hydrocarbons. In addition, Os isotopes afford vital insights into seawater Os fluctuations and
CUMMING, VIVIEN,MARY
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source