Results 131 to 140 of about 661,854 (360)
This work focuses on petrological-and-geochemical features, as well as age of dolerites widespread within the basins of the Mara, Kamenka and Uvat rivers.
I. А. Izbrodin +6 more
doaj +1 more source
Simultaneous determination of zircon U-Pb age and titanium concentration using LA-ICP-MS: Analysis data and crystallization temperature. [PDF]
Yuguchi T +7 more
europepmc +1 more source
Rb-Sr isotopic systematics of lherzolitic shergottite Yamato-793605 [PDF]
We have undertaken a Rb-Sr isotopic study of the lherzolitic shergottite, Yamato (Y)-793605. The acid-leaching experiment designed to remove secondary Pb contamination during previous work with U-Th-Pb systematics did not significantly affect the Rb-Sr ...
Kondorosi,Gabor +5 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
For the first time, zircons from thin volcanic ash layers contained within organic-rich black shales (Domanik facies) at the Devonian–Carboniferous boundary have been dated using the U–Pb LA-ICP-MS method.
V. V. Silantiev +7 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A database of detrital zircon geochronology ages of Cambrian to Paleogene deposits in South China
Complications of detrital zircons databases provide a means for statistically analysing a variety of significant geological problems. In this work, we tried to collect a database about the South China Phanerozoic detrital zircon geochronology data.
Tianle Xia +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

