Results 191 to 200 of about 50,766 (267)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Aortic pressure-velocity loop: a potential tool for assessing risk associated with midsystolic forward compression waves in patients with chronic atherosclerotic coronary artery disease. [PDF]

Am Heart J Plus
Hanya S, Yamakage H, Kondoh Y, Sugawara M.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Triplet regimens for frontline treatment of CLL-Great company or just a crowd? [PDF]

Hemasphere
McKeague S, Seymour JF.
europepmc   +1 more source

Analytical protocol for the U-Pb age determination on young zircons

Abstracts of Annual Meeting of the Geochemical Society of Japan, 2009
Hirata, Takafumi, Orihashi, Yuji, Okabayashi, Satoki, Yokoyama, Takaomi, Yokoyama, Tetsuya   +4 more
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Metal accumulation in paired colon cancer and adjacent tissues and its relationship with genotoxic and epigenetic biomarkers. [PDF]

Front Public Health
Al-Saleh I, Al-Qudaihi G, Al-Rouqi R, Alrushud N, Alnuwaysir H, Alhomoud S, Jabbar AA, Ashari L, Alahmadi R, Alkhdhur H, Falah SA, Almanea H, Alhussaini H, Semilan A, Althebaity R, Alharbi S.   +15 more
europepmc   +1 more source

Zircon U-Pb age of granite in the Oga Peninsula, Japan

Abstracts of Papers Presented at the Annual Meeting of The Japanese Association of Mineralogists, Petrologists and Economic Geologists, 2005
Ogasawara, Masatsugu, Shimoda, Gen, Morishita, Yuichi   +2 more
openaire   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Research on the imbalance of metal homeostasis and ferroptosis mechanisms in neurodegenerative diseases. [PDF]

Glob Med Genet
Zhang P, Jin W, Lyu X, Zhu S, Lu Y, Chen Y, Han L, Tao M, Li L.   +8 more
europepmc   +1 more source