Results 211 to 220 of about 189,480 (262)

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Genesis of zircon and its constraints on interpretation of U-Pb age

Chinese Science Bulletin, 2004
openaire   +1 more source

U‐Pb age of the Yxsjöberg Tungsten‐Skarn deposit, Sweden

GFF, 1994
Abstract The Yxsjoberg scheelite‐skam deposit of western Bergslagen (south‐central Sweden) formed in Palaeoproterozoic time when aqueous fluids migrating along lithologic discontinuities replaced limestones in acid volcanic rocks. The age of the mineralization and, thus, the source of the fluids are controversial.
Romer, R., Öhlander, B.
openaire   +4 more sources

A U–Pb age for mineralized Nipissing diabase, Gowganda, Ontario

Canadian Journal of Earth Sciences, 1986
Concordant baddeleyite and rutile analyses from mineralized Nipissing diabase at Gowganda's Castle mine yield a U–Pb age of [Formula: see text]. Baddeleyite is a primary phase of the diabase; therefore the age dates the magmatic emplacement. The genesis of rutile is less certain: rutile could have formed during an episode of alteration, veining, and ...
F. Corfu, A. J. Andrews
openaire   +2 more sources

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Interpretation of discordant U‐Pb zircon ages: An evaluation

Journal of Metamorphic Geology, 1997
The most widely used technique for the determination of high precision mineral growth ages in igneous and metamorphic rocks is dating of zircons with the U‐Pb method. The interpretation of these ages, particularly in metamorphic settings, is hampered by an incomplete understanding of the common phenomenon of partial Pb‐loss in zircon.
Mezger, Klaus, KROGSTAD, E. J.
openaire   +1 more source

U-Pb dating of a speleothem of Quaternary age

Geochimica et Cosmochimica Acta, 1998
We demonstrate that U-Pb dating is a promising method for secondary carbonate materials of Quaternary age and older by obtaining a 206Pb∗/238U age for a speleothem with high U (>10 μg g−1) and very low Pb (
Richards, DA, Bottrell, SH, Cliff, RA, Strohle, K, Rowe, PJ   +4 more
openaire   +1 more source