Contemporaneous mobile- and stagnant-lid tectonics on the Hadean Earth. [PDF]
NatureValley JW +11 more
europepmc +1 more source
U-Pb isotopic results for single shocked and polycrystalline zircons record 550-65.5-Ma ages for a K-T target site and 2700-1850-Ma ages for the Sudbury impact event [PDF]
The refractory mineral zircon develops distinct morphological features during shock metamorphism and retains these features under conditions that would anneal them in other minerals.
Bohor, B. F., Kamo, S. L., Krogh, T. E.
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
SHRIMP U-Pb Ages of the Namwon and Sunchang Granites [PDF]
The Journal of the Petrological Society of Korea, 2013 Hui Je Jo, Kye-Hun Park, Keewook Yi
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Reconstructing Eocene Antarctic river drainage from provenance analysis of Amundsen Sea embayment sediments. [PDF]
Sci AdvMarschalek JW +15 more
europepmc +1 more source
Recognition of the Kaweka Terrane in northern South Island, New Zealand: preliminary evidence from Rb–Sr metamorphic and U–Pb detrital zircon ages [PDF]
, 2011 CJ Adams +3 more
openalex +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Petrogenesis and tectonic significance of the Baipu granite porphyry in the Huangtian uranium deposit, northeastern Guangdong, South China. [PDF]
PLoS OneRuan K, Wu J, Long Z, Min Z.
europepmc +1 more source
Ion microprobe mass analysis of lunar samples. Lunar sample program [PDF]
Mass analyses of selected minerals, glasses and soil particles of lunar, meteoritic and terrestrial rocks have been made with the ion microprobe mass analyzer.
Anderson, C. A., Hinthorne, J. R.
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