Results 231 to 240 of about 668,632 (409)
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Tectonism rather than "snowball Earth" glaciation is responsible for the Great Unconformity. [PDF]
Zhan RR +11 more
europepmc +1 more source
Using in situ SHRIMP U-Pb Monazite and Xenotime Geochronology to Determine the Age of Orogenic Gold Mineralization: An Example from the Paulsens Mine, Southern Pilbara Craton [PDF]
Imogen O.H. Fielding
openalex +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Petrogenesis of Late Permian Mafic Rocks in the Western Guangxi Area, SW China: Implications for the Emeishan Mantle Plume Magmatism. [PDF]
Zhang Y, Zhang Z, Yuan Y.
europepmc +1 more source
Zircon U-Pb ages of debris from the basal ice of the Byrd ice core, central West Antarctica
Stuart N. Thomson +2 more
openalex +1 more source

