Results 81 to 90 of about 53,720 (266)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Turning Trash Into Treasure: Extracting Meaning From Discordant Data via a Dedicated Application

open access: yesGeochemistry, Geophysics, Geosystems
Zircon U–Pb geochronology is a vital tool for dating geological events, but interpreting discordant zircon ages—often the result of Pb loss due to fluid‐rock interactions—remains challenging.
Lucy M. Mathieson   +2 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Past the First Date: Ensemble Concordant–Discordant Comparison for Zircon Pb‐Loss Analysis

open access: yesGeochemistry, Geophysics, Geosystems
Zircon uranium–lead (U–Pb) geochronology is a cornerstone of Earth science for resolving the timing of deep‐time processes, yet the U–Pb system does not always behave as a closed chronometer.
Lucy M. Mathieson   +1 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

AGE AND PETROGENESIS OF DOLERITES ON THE MARA RIVER (SAYAN MARGINAL UPLIFT OF THE BASEMENT, SOUTHERN PART OF THE SIBERIAN CRATON)

open access: yesГеодинамика и тектонофизика
This work focuses on petrological-and-geochemical features, as well as age of dolerites widespread within the basins of the Mara, Kamenka and Uvat rivers.
I. А. Izbrodin   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Material composition of the Sharagol complex gabbro-diorite Late Paleozoic massifs of the Ungo-Khilok area, Central Transbaikalia, Russia

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов
The significance of the research is determined by the lack of information on the composition of rocks of the gabbro-diorite intrusion and their role in continental crust formation and the age of manifestation of basic- intermediate magmatism on this ...
Roza A. Badmatsyrenova   +1 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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