Results 101 to 110 of about 68,798 (308)

Earthtime Lesson Plan for U/Pb Dating (grade 8-12) [PDF]

The Earthtime Lesson Plan is a complete description of a radiometric dating module taught to high school students at MIT. U/Pd dating and it's uses, teacher background, materials needed, time frame and National Science Standards are all provided as well ...

core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Impacts of Common Lead on Apatite U-Pb Geochronology by LA-ICP-MS: Assessment and Correction Strategies

Yankuang ceshi
Apatite is a widespread U-bearing mineral in igneous, metamorphic, and sedimentary rocks. U-Pb geochronology of apatite can provide significant information for constraining magmatic evolution processes and tracing provenance.
Tao LUO, Hanlin WANG, Songbai ZHU, Liyuan QING, Zhaochu HU   +4 more
doaj   +1 more source

Is there a Grenvillian basement in the Guerrero-Morelos Platform of Mexico?

Geologica Acta, 2007
In the Guerrero-Morelos platform (Guerrero State, Mexico) the adakitic rocks of Early Tertiary age contain abundant hornblende-rich tonalite xenoliths. Zircon crystals have been concentrated from both adakites and xenoliths, and dated using in-situ U-Pb ...
G. Levresse, J. Tritlla, E. Deloule, P. J. PINTO LINARES   +3 more
doaj   +1 more source

Baddeleyite and zircon U-Pb ages of the ultramafic rocks in Chigu Tso area, Southeastern Tibet and their constraints on the timing of Comei Large Igneous Province

China Geology, 2020
: A suite of ultramafic and mafic rocks developed in the Chigu Tso area, eastern Tethyan Himalaya. Baddeleyite and zircon U-Pb ages acquired by SIMS and LA-ICP-MS from olivine pyroxenite rocks in the Chigu Tso area are 138.9±3.0 Ma and 139.0±1.9 Ma ...
Ya-ying Wang, Ling-sen Zeng, Ling-hao Zhao, Li-e Gao, Jia-hao Gao, Zhao-ping Hu, Hai-tao Wang, Guang-xu Li, Ying-long Di, Yu Shen, Qian Xu   +10 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Zircon U-Pb dating of Mesozoic volcanic and tectonic events in northwest Palmer Land and southwest Graham Land, Antarctica [PDF]

, 2009
New whole rock Rb-Sr and zircon U-Pb geochronological data and Sm-Nd isotopic data are presented from the central magmatic arc domain of the Antarctic Peninsula in the area of northwest Palmer Land and southwest Graham Land, Rb-Sr isochrons indicate an ...
Flowerdew, Michael, Leat, Philip, Millar, Ian, Riley, Teal, Scarrow, J.H., Whitehouse, M.J.   +5 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

In situ rutile U-Pb dating by laser ablation-MC-ICPMS

GEOCHEMICAL JOURNAL, 2013
Copyright © 2013 by The Geochemical Society of Japan. et al. (2007), Zack et al. (2011) and Kooijman et al. (2010). This method is limited to rutile grains with sufficient U in order to get suitable Pb signal intensity (Zack et al., 2011). It is well known that multi collector ICPMS offers advantages in terms of higher sensitivity, flat top peak shape ...
Ren, Z, Xia, X, Wei, G, Zhang, L, Sun, M, Wang, Y   +5 more
openaire   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source