Results 131 to 140 of about 151,775 (355)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

U-Pb dating and geochemical dataset of fracture-filling calcite veins from the Bóixols-Sant Corneli anticline (Southern Pyrenees). [PDF]

open access: yesData Brief, 2022
Muñoz-López D   +10 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Electron microprobe dating of lunar zirconolite

open access: yesJournal of Analytical Science and Technology
Zirconolite is an accessary mineral occurred in the lunar basaltic and granitic rocks and contains relatively high contents of U, Th, and Pb, which is attractive for age dating.
Changkun Park, Hwayoung Kim
doaj   +1 more source

Gemological and Chemical Characterization of Gem-Quality Titanite from Morocco

open access: yesCrystals
Titanite is a widespread accessory mineral in igneous, metamorphic, and hydrothermal rocks, but few comply with gem-grade requirements. Previous studies on Moroccan titanite focused on elementary composition and U-Pb dating.
Yu Yuan   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

U-Th-Pb Dating of Monazite by LA-ICP-MS Using Ablation Spot Sizes of 16 μm and 10 μm

open access: yesYankuang ceshi, 2016
Monazite is a common geological chronometer and has complex textures and different chemical domains. Meaningful U-Th-Pb ages for different domains can be obtained only using a suitably small laser beam spot.
WANG Shuang-shuang   +5 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Dating of ice cores from Vernagtferner (Austria) with fission products and lead-210 [PDF]

open access: yes, 1982
Fission product (90Sr_ 90y, I37CS, total beta) and 2tOPb_210pO activities were measured in core samples from the temperate vernagtferner (3150 m altitude, Oetztal Alps, Austria).
Gäggeler, Heinz   +2 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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