Results 191 to 200 of about 15,214,902 (294)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...Eloise Mastrangelo, Flavio Di Pisawiley +1 more sourceLong-Baseline Neutrino Facility (LBNF) and Deep Underground Neutrino Experiment (DUNE) Conceptual Design Report Volume 1: The LBNF and DUNE Projects
, 2015 R. Acciarri, S. Bansal, A. Friedland, Z. Djurcic, L. Rakotondravohitra, T. Xin, E. Mazzucato, C. Densham, E. Calvo, S. Li, C. Mishra, Acero, A. Zalewska, M. Adamowski, N. Spooner, N. Walsh, A. Palazzo, R. Gran, J. Stewart, G. Brooijmans, T. Patzak, J. Navarro, K. Yonehara, J. Moon, R. Roser, D. Girardelli, A. Ankowski, V. Radeka, E. Tziaferi, A. Topkar, P. Mehta, M. Wilking, O. Palamara, C. Moura, J. Davies, J. Mousseau, L. Periale, H. Sobel, M. Thomson, D. Dwyer, T. Usher, C. Jackson, T. Gamble, S. Golapinni, K. Riesselmann, T. Haines, M. Chen, P. D. Jong, C. Rohr, A. Rappoldi, J. Musser, J. Valle, M. Cascella, L. Suter, D. Lee, B. Zamorano, M. Vagins, N. Mokhov, H. Duyang, A. Kostelecky, P. Shanahan, J. Osta, Siqi Yang, Y. Ramachers, E. Amador, W. Marciano, J. Schneps, L. Paulucci, J. Joshi, R. Mohanta, T. Hamernik, I. Stancu, J. Park, J. Johnstone, C. Regenfus, J. Heise, Kevin C. Lee, D. Whittington, L. Rochester, F. Sanchez, T. V. Vieira, D. Stefan, S. Malhotra, E. Pennacchio, X. Qian, S. Manly, D. Malon, T. Grundy, R. Petti, M. Worcester, N. McConkey, R. Bernstein, M. Kirby, D. Jaffe, S. Söldner-Rembold, T. Boone, K. Yarritu, A. Weber, A. Perch, S. Elliott, X. Bu, C. Vilela, R. Schmitt, W. Kropp, B. Behera, M. Elnimr, M. Bergevin, A. Habig, R. Talaga, B. Yu, G. Raffelt, R. Rucinski, B. Kayser, C. Bromberg, R. Corey, F. Noto, S. Stoica, J. Anderson, K. Hennessy, S. Pakvasa, J. Libo, S. Striganov, D. Mertins, V. Guarino, X. Li, E. Pantic, Z. Ahmad, M. Torti, A. Farbin, M. Headley, N. Benekos, A. Fernandez, V. Bocean, R. Nichol, J. Fowler, J. Beacom, H. Schellman, L. Littenberg, T. Miao, C. Mariani, Y. Meng, C. James, S. Jiménez, P. Vahle, H. O’Keeffe, E. Kemp, M. Rossella, N. Barros, G. Barr, J. Maricic, R. Sharma, J. Asaadi, X. Tian, A. Khotjantsev, A. Kaur, B. Bleakley, S. Rescia, J. Ramsey, C. Marshall, B. Page, K. Rielage, A. Rubbia, M. Tzanov, A. Kumar, W. Morse, S. Horikawa, J. Ye, J. J. G. Cadenas, N. Graf, A. White, S. Timm, J. Klein, T. Liu, T. Bolton, D. Montanari, O. Miranda, G. Pawloski, J. D. Jong, N. Simos, B. Jones, K. Mahn, M. Groh, M. Bonesini, T. Ovsjannikova, W. Fox, J. Sepulveda-Quiroz, S. Seibert, A. Guglielmi, C. Castromonte, M. Ross-Lonergan, N. Kazaryan, F. Tortorici, B. Bhandari, M. Borysova, M. Zito, R. Dharmapalan, M. Soderberg, A. Ariga, J. LoSecco, E. Hazen, J. Nowak, A. Kaboth, R. Guenette, T. B. Watson, R. Rameika, C. Chi, E. Blucher, A. Weinstein, V. Gehman, S. Fernandes, J. Strait, A. Hahn, L. Favilli, L. Corwin, J. Stock, A. Delbart, D. Aristizabal, K. Terao, P. Snopok, Z. Liptak, P. Benetti, W. Wei, A. Giri, K. Soustruznik, J. Anjos, F. Cavanna, R. Gomes, B. Rebel, A. Holin, B. Fleming, C. Cantini, J. Napolitano, R. Gill, M. Fitton, S. Kemboi, T. Loew, L. Kormos, M. Johnson, N. Poudyal, A. Brandt, E. Kearns, A. Sousa, A. Heavey, M. Mewes, Venktesh Singh, D. Cherdack, J. Reichenbacher, Y. Sun, P. Wilson, O. Mineev, G. Raselli, M. Graham, B. Paulos, S. Menary, J. Zálešák, M. Marshak, J. Lowery, D. Reitzner, G. Koizumi, D. Mcnulty, S. Hans, Cabot-Ann Christofferson, S. Bertolucci, S. Mishra, A. Cocco, A. Ereditato, J. Dawson, A. Scaramelli, Leigui de Oliveira, G. Sinnis, J. Coelho, L. Thompson, G. Meng, J. Matthews, M. Tamsett, R. Tsenov, A. Blake, T. Junk, T. Vrba, M. Tripathi, G. Garvey, C. Taylor, Sudeep Das, V. Paolone, Athar, C. Booth, J. Hylen, A. Bercellie, Y. Onishchuk, S. Ventura, T. Tope, A. Gago, B. Baibussinov, T. Wąchała, D. Garcia-Gamez, S. Lin, M. Baird, D. Gibin, E. Tatar, M. Rosen, Y. Nakajima, Z. Vallari, S. Parke, S. Brice, C. Tull, M. Campanelli, L. Sexton-Kennedy, S. Emery, V. Papadimitriou, C. Albright, R. Johnson, H. Lee, P. Sala, J. Boissevain, J. Martín-Albo, S. Wu, J. Stone, G. Karagiorgi, O. Prokofiev, G. Geronimo, P. Rodrigues, R. Hatcher, M. Robinson, J. Insler, A. Mann, J. Hartnell, H. Berns, A. Verdugo, B. Kirby, M. Thiesse, M. Auger, M. Yeh, D. Lissauer, S. Patton, R. Andrews, A. Menegolli, G. Brown, W. Honey, K. Iwamoto, S. Adhikari, M. Wascko, A. Himmel, J. Urheim, J. Conrad, S. Chattopadhyay, L. Wang, D. Autiero, X. Bai, M. Bishai, P. Wittich, S. Childress, T. Viant, S. Pal, L. Greenler, C. Morris, C. Jung, S. Fuess, D. Taylor, R. Oldeman, R. Kadel, R. Santorelli, H. Steiner, G. Velev, L. Kalousis, J. Singh, A. Tonazzo, W. M. Lee, D. Martinez, T. Blackburn, D. Wahl, H. Merritt, P. D. Lurgio, E. Berman, R. Berg, C. Greenley, M. Potekhin, T. Warburton, R. Potenza, A. Izmaylov, R. Plunkett, J. Raaf, G. Petrillo, L. Mualem, J. Kumar, V. Aushev, N. Grant, D. Mladenov, C. Palomares, H. Jöstlein, T. Kafka, C. Mauger, A. Petukhov, N. Sahu, S. Tariq, K. Wood, P. Adamson, G. Christodoulou, S. Peeters, E. Segreto, M. Thorpe, G. Perdue, G. Bautista, C. Lin, C. Lane, N. Dhingra, K. Tsang, K. Lang, T. Handler, B. Balantekin, D. Mei, E. Church, D. Edmunds, S. Dytman, R. Kriske, H. Rakotondramanana, Y. Kamyshkov, L. Bartoszek, D. Pushka, E. Worcester, F. Bay, J. Lykken, D. Karasavvas, B. Baller, M. Avila, L. Falk, M. Sorel, Q. Liu, A. Mefodiev, A. Laminack, S. Goswami, J. Shahi, M. Toups, M. Khabibullin, C. Vignoli, S. Boyd, A. Falcone, T. Ariga, W. Louis, K. Long, M. Richardson, K. Vaziri, G. Varner, J. Dolph, R. Oliveira, Y. Ng, M. Chalifour, D. Harris, H. Wang, A. Kopylov, D. Wenman, R. Brown, M. Kordosky, M. Diwan, K. Anderson, K. Biery, E. Niner, A. Remoto, B. Littlejohn, W. Miller, W. Metcalf, M. Krämer, P. Novakova, J. Schwehr, F. Boffelli, C. Escobar, P. Calafiura, A. Radovic, A. Marino, D. Tiedt, B. Choudhary, D. Duchesneau, Qizhong Li, K. Mavrokoridis, J. Diaz, Z. Li, J. Lopez, S. Luise, R. Patterson, R. V. D. Water, M. Nessi, D. Wells, A. McGowan, O. Mena, C. Montanari, R. Saakyan, T. Olson, A. Finch, F. Varanini, N. McCauley, U. Kose, M. Andrews, B. Fujikawa, J. Perkin, G. Introzzi, J. Thomas, K. Grzelak, P. Schlabach, M. DuVernois, E. Guarnaccia, A. D. Gouvea +499 moresemanticscholar +1 more sourceβ‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón +8 morewiley +1 more sourceNicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu +5 morewiley +1 more source
