Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Characterization of Strategic Deconflicting Service Impact on Very Low-Level Airspace Capacity
European airspace is poised for significant transformation as it prepares to accommodate a new class of unmanned traffic that will reshape the transport of people and goods.
Zhiqiang Liu +2 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Public space performs. Creative explorations of performativity in public space [extended article] [PDF]
This article is an extended contribution from a paper originally presented as part of the 2024 conference Past, Present and Future of Public Spacein Bologna,promoted by City Space Architecture, under the same title.
City Space Architecture +1 more
core +1 more source
Moduli spaces of instantons in flag manifold sigma models. Vortices in quiver gauge theories
In this paper, we discuss lumps (sigma model instantons) in flag manifold sigma models. In particular, we focus on the moduli space of BPS lumps in general Kähler flag manifold sigma models. Such a Kähler flag manifold, which takes the form U n 1 + ⋯ + n
Toshiaki Fujimori +2 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Agile in Orbit: Enabling Our Mission Partners to Thrive in the Ever-Changing Space Domain
At SDL, agility is a quality of both our mission approach and our space ...
Space Dynamics Laboratory
core +1 more source
Regularity of weak solutions of the Navier-Stokes equations near the smooth boundary
Any weak solution u of the Navier-Stokes equations in a bounded domain satisfying the Prodi-Serrin's conditions locally near the smooth boundary cannot have singular points there.
Zdenek Skalak
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

