Results 121 to 130 of about 481,772 (339)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
In this paper, we present high-resolution image and video CubeSat (HiREV), the first constructed 6 U platform to reach the space technology test bed stage, developed by the Korea Aerospace Research Institute (KARI).
Dong-Hyun Cho +5 more
doaj +1 more source
A Self-Heuristic Ant-Based Method for Path Planning of Unmanned Aerial Vehicle in Complex 3-D Space With Dense U-Type Obstacles [PDF]
Chao Zhang +5 more
openalex +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
TRAVELING WAVE SOLUTIONS OF SOME FRACTIONAL DIFFERENTIAL EQUATIONS [PDF]
The modified Kudryashov method is powerful, efficient and can be used as an alternative to establish new solutions of different type of fractional differential equations applied in mathematical physics.
SERIFE MUGE EGE, EMINE MISIRLI
doaj
On the weak solution $u ∈ C_1-α(I,E) of a fractional-order weighted Cauchy type problem in reflexive Banach spaces [PDF]
A. M. A. El-Sayed +1 more
openalex +1 more source
Towards Autonomous Multi-UAV U-Space Operation Planning
One of the main challenges in the real-world adoption of multi-Uncrewed Aerial Vehicle (UAV) systems lies in the specification of operations and the management of dynamic tasks in varied operational contexts. In this paper, we propose a multi-UAV planning architecture to reduce the level of specialized expertise necessary for handling multi-UAV systems.
Grøntved, Kasper A.R. +5 more
openaire +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

