Results 141 to 150 of about 481,772 (339)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Le Matematiche, 2007 We consider a measure valued map α(u) defined on D where D is a subspace of L^p(X,m) with X a locally compact Hausdorff topological space with a distance under which it is a space of homogeneous type.
Marco Biroli, Paola Vernole
doaj
Spectral gaps for the O-U/Stochastic heat processes on path space over a Riemannian manifold with boundary [PDF]
, 2018 Bo Wu
openalex +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Counterexamples for the space of minimal solutions of the equation $\Delta u=Pu$ on a Riemann surface. [PDF]
, 1975 Y.K. Kwon, J. L. Schiff
openalex +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Bessel-type inequalities in semi-Hilbert spaces with applications to operator tuples
Journal of Inequalities and ApplicationsConsider a non-zero positive operator A on a complex Hilbert space ( H , 〈 ⋅ , ⋅ 〉 ) $(\mathfrak{H}, \langle \cdot , \cdot \rangle )$ . This operator induces an A-semi-inner product defined by ( u ∣ v ) A : = 〈 A u , v 〉 $(u \mid v)_{\mathbf{A ...
Feryal Aladsani +3 more
doaj +1 more source
Uniqueness/nonuniqueness for nonnegative solutions of the Cauchy problem for $u_t=Δu-u^p$ in a punctured space [PDF]
, 2004 Ross G. Pinsky
openalex +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source