Results 71 to 80 of about 481,772 (339)
Affine Grassmannians of group schemes and exotic principal bundles over A¹
Let G be a simple simply-connected group scheme over a regular local scheme U. Let E be a principal G-bundle over A^1_U trivial away from a subscheme finite over U. We show that E is not necessarily trivial and give some criteria of triviality.
Fedorov, R.
core +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Type B 3-fold Supersymmetry and Non-polynomial Invariant Subspaces
We obtain the most general type B 3-fold supersymmetry by solving directly the intertwining relation. We then show that it is a necessary and sufficient condition for a second-order linear differential operator to have three linearly independent local ...
Tanaka, Toshiaki
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Turbulence without pressure in d dimensions
The randomly driven Navier-Stokes equation without pressure in d-dimensional space is considered as a model of strong turbulence in a compressible fluid. We derive a closed equation for the velocity-gradient probability density function.
A. Chekhlov +16 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
We consider the problem of performing predecessor searches in a bounded universe while achieving query times that depend on the distribution of queries.
Bose, Prosenjit +3 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
U-space separation management service: concept definition and validation
Over the last decade, the unmanned aircraft industry has attracted a great deal of interest due to its potential and multitude of applications, especially in urban environments. This has led authorities and the general public to raise different issues and concerns, among which safety is the most prevalent.
Claramunt Puchol, Cecilia +3 more
openaire +1 more source

