Results 71 to 80 of about 8,623,503 (244)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
OzFuel Phase A Study Report: Space-based Australian Forest Fuel Flammability Monitoring
, 2022 • This work reports on the 14th concurrent engineering study conducted at UNSW Canberra Space Australian National Concurrent Design Facility (ANCDF) during a 5-day workshop on 21-25 February 2022.
UNSW Canberra Space
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A Tactical Conflict Resolution Proposal for U-Space Zu Airspace Volumes. [PDF]
Sensors (Basel), 2021 Jover J, Bermúdez A, Casado R.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2014 Wits Architecture Student Works 1922-1980. Tomaselli, U R. Church, scale working drawings. BArch III 1937; Space & Structure. BArch V 1939Wits Architecture Student Works 1922-1980. Tomaselli, U R. Church, scale working drawings. BArch III 1937; Space
Tomaselli, U R
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Flavored resonant leptogenesis in the U(1)X model
Nuclear Physics BWe study the generation of baryon asymmetry through the flavored resonant leptogenesis in the U(1)X extension of the Standard Model. Being a generalization of the U(1)B-L, U(1)X is an ultraviolet-complete model of the right-handed neutrinos (RHNs), whose
Garv Chauhan
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Jefferson County Open Space Master Plan
, 2022 COMMUNITY RESOURCES - OPEN SPACE - ADOPTION OF THE JEFFERSON COUNTY OPEN SPACE MASTER PLAN Approval of the Open Space Five Year Master Plan by the Board of County Commissioners.
Jefferson County Open Space (Program);
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Spatiotemporal distribution of ionospheric irregularities over India during St. Patrick’s Day Storm [PDF]
, 2022 The irregularities formed over the equatorial ionospheric region over the Indian sector have been studied for the first time for the day of the most intense geomagnetic storm of solar cycle-24, which occurred on 17.03.2015, using Rate of TEC Index (ROTI)
Acharya, Rajat ; Space Applications Centre, Ahmedabad Indian Space Research Organization
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source