Results 241 to 250 of about 11,479,816 (281)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tissue-specific variability in protein expression of cytochrome P450 and glutathione S-transferase isoenzymes in non-small cell lung carcinoma. [PDF]

Arh Hig Rada Toksikol
Kılıç M, Oğuztüzün S, Çelik S, Demirağ F, Bıçakçıoğlu P, İşcan M, Ada AO.   +6 more
europepmc   +1 more source

Application of Deep Learning Algorithm-Based Image Reconstruction in Improving Abdominal CT Image Quality in Adrenal and Renal Lesions Detection. [PDF]

Radiol Res Pract
Tian J, Yao H, Cao C, Zhang P, Wang S, Kang M, Cui H, Wu S.   +7 more
europepmc   +1 more source