Results 81 to 90 of about 48,763 (192)
Tau PET overlap index correlation with neuropathological findings
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION
The tau positron emission tomography (PET) overlap index (OI) has shown promise in maximizing signal‐to‐noise for longitudinal tau PET imaging, particularly for early tau pathology, but requires validation against neuropathology.Seokbeen Lim, Jeyeon Lee, Paul H. Min, Christina M. Moloney, Carly T. Mester, Sujala Ghatamaneni, Matthew L. Senjem, Hugo Botha, David S. Knopman, Stuart J. McCarter, Vijay K. Ramanan, Rodolfo Savica, Julie A. Fields, Mary M. Machulda, Dennis W. Dickson, R. Ross Reichard, Aivi T. Nguyen, Jonathan Graff‐Radford, Christopher G. Schwarz, Jeffrey L. Gunter, Kejal Kantarci, Bradley Boeve, Prashanthi Vemuri, David T. Jones, Clifford R. Jack Jr., Ronald C. Petersen, Melissa E. Murray, Val J. Lowe +27 morewiley +1 more sourceThe landscape of dementia research, diagnosis, treatment, and care in Latin America
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.Claudia K. Suemoto, Nilton Custodio, Diego Aguilar, José A. Avila‐Funes, Sandra Baez, Pablo M. Bagnati, Lisa L. Barnes, Sonia M. D. Brucki, Ismael L. Calandri, Paulo Caramelli, Mario Cornejo‐Olivas, Carolina Delgado Derio, Sergio T. Ferreira, Adolfo M. García, Lea T. Grinberg, Agustin M. Ibanez, Rosario Isasi, Sylvia E. Josephy‐Hernández, Maria Lazo Porras, Jorge J. Llibre‐Guerra, Juan J. Llibre‐Rodriguez, Mychael V. Lourenco, B. Marcela Mar Meza, Joaquin Migeot, J. Jaime Miranda, Claudia Miranda‐Castillo, Catherine J. Mummery, José F. Parodi, Natalia Pozo Castro, Rosa María Salinas Contreras, Hernando Santamaría‐García, Andrea Slachevsky, Juliana N. Souza‐Talarico, Ezequiel I. Surace, Leonel T. Takada, Elena Tsoy, Martha Unaucho Pilalumbo, Eduardo R. Zimmer, Igor C Fontana, Simin Mahinrad, Heather M. Snyder, Maria C. Carrillo +41 morewiley +1 more sourceThere are Plane Spanners of Maximum Degree 4
, 2014 Let E be the complete Euclidean graph on a set of points embedded in the
plane. Given a constant t >= 1, a spanning subgraph G of E is said to be a
t-spanner, or simply a spanner, if for any pair of vertices u,v in E the
distance between u and v in G is ...Bonichon, Nicolas, Kanj, Iyad, Perković, Ljubomir, Xia, Ge +3 morecore +2 more sourcesAmyloid‐related default mode network hyperconnectivity and longitudinal decline in network distinctiveness in preclinical Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION
We investigated stage‐specific alterations in functional connectivity (FC) of the default mode network (DMN) across the Alzheimer's disease (AD) continuum and tested whether early amyloid beta (Aβ)–related changes in within‐DMN FC (DMN‐FCwithin) predicted longitudinal alterations in DMN between‐network connectivity (DMN‐FCbetween).Woo‐Jin Cha, Evgeny J. Chumin, Dahyun Yi, Min Soo Byun, Joon Hyung Jung, Hyejin Ahn, Gijung Jung, Yu Kyeong Kim, Yun‐Sang Lee, Koung Mi Kang, Chul‐Ho Sohn, Shannon L. Risacher, Olaf Sporns, Kwangsik Nho, Andrew J. Saykin, Dong Young Lee, for the KBASE Research Group +16 morewiley +1 more sourceAssociation between brain volume and depression in Alzheimer's disease: Neuroimaging insights
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION
Alzheimer's disease (AD) often co‐occurs with depression, affecting cognitive function and quality of life. Understanding the neurobiological links between brain abnormalities and depressive symptoms is essential for effective treatment.Chao Tang, Jiaxin Yang, Xiaoyang Lei, Ming Zhang, Yi Chen, Xiaoxue Peng, Dian He +6 morewiley +1 more sourceAI‐enhanced Centiloid quantification of amyloid PET images
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION
The Centiloid scale is the standard for amyloid (Aβ) PET quantification in research and clinical settings. However, variability between tracers and scanners remains a challenge. METHODS
This study introduces DeepSUVR, a deep learning method to correct Centiloid quantification, by penalizing implausible longitudinal trajectories ...Pierrick Bourgeat, Jurgen Fripp, Leo Lebrat, Ying Xia, Azadeh Feizpour, Timothy Cox, Georgios Zisis, Ashley Gillman, Manu S. Goyal, Duygu Tosun, Tammie LS. Benzinger, Pamela LaMontagne, Michael Breakspear, Michelle K. Lupton, Cathy Short, Robert Adam, Joanne S. Robertson, Reisa Sperling, Sid E. O'Bryant, Sterling C. Johnson, Clifford R. Jack Jr, Christopher G. Schwarz, Frederik Barkhof, Gill Farrar, Ariane Bollack, Lyduine E. Collij, Susan Landau, Robert Koeppe, for the Alzheimer's Disease Neuroimaging Initiative, OASIS3, the A4/LEARN Study Team, the AMYPAD consortium, The Health and Aging Brain Study (HABS‐HD) Study Team, Mayo Clinic Study of Aging, WRAP, ADNI‐DOD, PISA, ADNeT, the AIBL research group, John C. Morris, Michael W. Weiner, Victor L. Villemagne, Colin L. Masters, Christopher C. Rowe, Vincent Dore +44 morewiley +1 more sourceA network analysis to identify mediators of germline-driven differences in breast cancer prognosis. [PDF]
, 2020 Identifying the underlying genetic drivers of the heritability of breast cancer prognosis remains elusive. We adapt a network-based approach to handle underpowered complex datasets to provide new insights into the potential function of germline variants ...Abraham, Jean, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker, Ashworth, Alan, Auer, Paul L, Auvinen, Päivi, Beckmann, Matthias W, Beesley, Jonathan, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Blot, William, Bogdanova, Natalia V, Bojesen, Stig E, Bolla, Manjeet K, Brauch, Hiltrud, Brenner, Hermann, Brucker, Sara Y, Burwinkel, Barbara, Børresen-Dale, Anne-Lise, Caldas, Carlos, Canzian, Federico, Chang-Claude, Jenny, Chanock, Stephen J, Chin, Suet-Feung, Clarke, Christine L, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Dennis, Joe, Devilee, Peter, Dunn, Janet A, Dunning, Alison M, Dwek, Miriam, Earl, Helena M, Eccles, Diana M, Eliassen, A Heather, Ellberg, Carolina, Escala-Garcia, Maria, Evans, D Gareth, Fasching, Peter A, Figueroa, Jonine, Flyger, Henrik, Gago-Dominguez, Manuela, Gapstur, Susan M, García-Closas, Montserrat, García-Sáenz, José A, Gaudet, Mia M, George, Angela, Giles, Graham G, Goldgar, David E, González-Neira, Anna, Grip, Mervi, Guo, Qi, Guénel, Pascal, Haiman, Christopher A, Hamann, Ute, Harrington, Patricia A, Hiller, Louise, Hooning, Maartje J, Hopper, John L, Howell, Anthony, Huang, Chiun-Sheng, Huang, Guanmengqian, Hunter, David J, Håkansson, Niclas, Jakubowska, Anna, John, Esther M, Kaaks, Rudolf, Kapoor, Pooja Middha, Keeman, Renske, Kitahara, Cari M, Koppert, Linetta B, Kraft, Peter, Kristensen, Vessela N, Lambrechts, Diether, Le Marchand, Loic, Lejbkowicz, Flavio, Lindblom, Annika, Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Manoukian, Siranoush, Margolin, Sara, Martinez, Maria Elena, Maurer, Tabea, Mavroudis, Dimitrios, Meindl, Alfons, Milne, Roger L, Mulligan, Anna Marie, Neuhausen, Susan L, Nevanlinna, Heli, Newman, William G, Olshan, Andrew F, Olson, Janet E, Olsson, Håkan +99 morecore