Results 41 to 50 of about 16,532,252 (340)
Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction
Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods
We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda +15 morewiley +1 more sourceSequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang +10 morewiley +1 more sourceDisturbances of metabolic homeostasis is liver disease.
Acta Médica Portuguesa, 1981
The liver occupies a major role in metabolic homeostasis with important functions in carbohydrate, fat and protein metabolism. Abnormalities in glucose homeostasis are common in all forms of liver disease although fasting hypoglycaemia is surprisingly ...K. G. M. M. Alberti, D. G. Johnston, M. Piniewska-Hulas, J. Whittaker +3 moredoaj +1 more sourceAngular Analysis of the B^{+}→K^{*+}μ^{+}μ^{-} Decay.
Physical Review Letters, 2021 We present an angular analysis of the B^{+}→K^{*+}(→K_{S}^{0}π^{+})μ^{+}μ^{-} decay using 9 fb^{-1} of pp collision data collected with the LHCb experiment.R. Aaij, C. Beteta, T. Ackernley, B. Adeva, M. Adinolfi, H. Afsharnia, C. Aidala, S. Aiola, Z. Ajaltouni, S. Akar, J. Albrecht, Federico Alessio, M. Alexander, A. A. Albero, Z. Aliouche, G. Alkhazov, P. Cartelle, S. Amato, Y. Amhis, L. An, L. Anderlini, A. Andreianov, M. Andreotti, F. Archilli, A. Artamonov, M. Artuso, K. Arzymatov, E. Aslanides, M. Atzeni, B. Audurier, S. Bachmann, M. Bachmayer, J. Back, S. Baker, P. Rodriguez, V. Balagura, W. Baldini, J. B. Leite, R. Barlow, S. Barsuk, W. Barter, M. Bartolini, F. Baryshnikov, J. Basels, G. Bassi, B. Batsukh, A. Battig, A. Bay, M. Becker, F. Bedeschi, I. Bediaga, A. Beiter, V. Belavin, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, D. Berninghoff, H. C. Bernstein, C. Bertella, A. Bertolin, C. Betancourt, F. Betti, I. Bezshyiko, S. Bhasin, J. Bhom, L. Bian, M. Bieker, S. Bifani, P. Billoir, M. Birch, F. Bishop, A. Bizzeti, M. Bjørn, M. Blago, T. Blake, F. Blanc, S. Blusk, D. Bobulska, J. Boelhauve, O. B. Garcia, T. Boettcher, A. Boldyrev, A. Bondar, N. Bondar, S. Borghi, M. Borisyak, M. Borsato, J. Borsuk, S. A. Bouchiba, T. Bowcock, A. Boyer, C. Bozzi, M. Bradley, S. Braun, A. Rodriguez, M. Brodski, J. Brodzicka, A. B. Gonzalo, D. Brundu, A. Buonaura, C. Burr, A. Bursche, A. Butkevich, J. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, L. Calefice, L. Diaz, S. Calí, R. Calladine, M. Calvi, M. C. Gomez, P. Magalhães, A. Camboni, P. Campana, A. F. C. Quezada, S. Capelli, L. Capriotti, A. Carbone, G. Carboni, R. Cardinale, A. Cardini, I. Carli, P. Carniti, K. Akiba, A. Vidal, G. Casse, M. Cattaneo, G. Cavallero, S. Celani, J. Cerasoli, A. Chadwick, M. Chapman, M. Charles, P. Charpentier, G. Chatzikonstantinidis, C. Barajas, M. Chefdeville, C. Chen, S. Chen, A. Chernov, S. Chitic, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, M. Cicala, X. Vidal, G. Ciezarek, P. Clarke, M. Clemencic, H. Cliff, J. Closier, J. Cobbledick, V. Coco, J. Coelho, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, L. Congedo, A. Contu, N. Cooke, G. Coombs, G. Corti, C. M. Sobral, B. Couturier, D. Craik, J. Crkovská, M. C. Torres, R. Currie, C. Da Silva, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, A. Danilina, P. d’Argent, A. Davis, O. Francisco, K. De Bruyn, S. De Capua, M. De Cian, J. De Miranda, L. De Paula, M. De Serio, D. De Simone, P. De Simone, J. de Vries, C. Dean, W. Dean, D. Decamp, L. Del Buono, B. Delaney, H. Dembinski, A. Dendek, V. Denysenko, D. Derkach, O. Deschamps, F. Desse, F. Dettori, B. Dey, P. Di Nezza, S. Didenko, L. Maronas, H. Dijkstra, V. Dobishuk, A. Donohoe, F. Dordei, A. dos Reis, L. Douglas, A. Dovbnya, A. Downes, K. Dreimanis, M. Dudek, L. Dufour, V. Duk, P. Durante, J. Durham, D. Dutta, M. Dziewiecki, A. Dziurda, A. Dzyuba, S. Easo, U. Egede, V. Egorychev, S. Eidelman, S. Eisenhardt, S. Ek-In, L. Eklund, S. Ely, A. Ene, E. Epple, S. Escher, J. Eschle, S. Esen, T. Evans, A. Falabella, J. Fan, Y. Fan, B. Fang, N. Farley, S. Farry, D. Fazzini, P. Fedin, M. Feo, P. F. Declara, A. F. Prieto, J. M. Arribas, F. Ferrari, L. Lopes, F. Rodrigues, S. F. Sole, M. Ferrillo, M. Ferro-Luzzi, Sergey Filippov, R. Fini, M. Fiorini, M. Firlej, K. Fischer, C. Fitzpatrick, T. Fiutowski, F. Fleuret, M. Fontana, F. Fontanelli, R. Forty, V. F. Lima, M. F. Sevilla, M. Frank, E. Franzoso, G. Frau, C. Frei, D. A. Friday, J. Fu, Q. Fuehring, W. Funk, E. Gabriel, T. Gaintseva, A. Torreira, D. Galli, S. Gambetta, Y. Gan, M. Gandelman, P. Gandini, Y. Gao, M. Garau, L. Martin, P. Moreno, J. García Pardiñas, B. G. Plana, F. G. Rosales, L. Garrido, C. Gaspar, R. Geertsema, D. Gerick, L. L. Gerken, E. Gersabeck, M. Gersabeck, T. Gershon, D. Gerstel, P. Ghez, V. Gibson, M. Giovannetti, A. Gioventù, P. G. Gironell, L. Giubega, C. Giugliano, K. Gizdov, E. Gkougkousis, V. Gligorov, C. Göbel, E. Golobardes, D. Golubkov, A. Golutvin, A. Gomes, S. Fernandez, F. G. Abrantes, M. Goncerz, G. Gong, P. Gorbounov, I. Gorelov, C. Gotti, E. Govorkova, J. Grabowski, R. Diaz, T. Grammatico, L. Cardoso, E. Grauges, E. Graverini, G. Graziani, A. Grecu, L. M. Greeven, P. Griffith, L. Grillo, S. Gromov, B. R. G. Cazon, C. Gu, Marco Guarise, P. Günther, E. Gushchin, A. Guth, Y. Guz, T. Gys, T. Hadavizadeh, G. Haefeli, C. Haen, J. Haimberger, T. Halewood-leagas, P. Hamilton, Q. Han, X. Han, T. Hancock, S. Hansmann-Menzemer, N. Harnew, T. Harrison, C. Hasse, M. Hatch, J. He, M. Hecker, K. Heijhoff, K. Heinicke, A. Hennequin, K. Hennessy, L. Henry, J. Heuel, A. Hicheur, D. Hill, M. Hilton, S. Hollitt, J. Hu, J. Hu, W. Hu, W. Huang, X. Huang, W. Hulsbergen, R. Hunter, M. Hushchyn, D. Hutchcroft, D. Hynds, P. Ibis, M. Idzik, D. Ilin, P. Ilten, A. Inglessi, A. Ishteev, K. Ivshin, R. Jacobsson, S. Jakobsen, E. Jans, B. Jashal, A. Jawahery, Vukan Jevtic, M. Jeżabek, F. Jiang, M. John, D. Johnson, C. Jones, T. Jones, B. Jost, N. Jurik, S. Kandybei, Y. Kang, M. Karacson, N. Kazeev, F. Keizer, M. Kenzie, T. Ketel, B. Khanji, A. Kharisova, S. Kholodenko, K. Kim, T. Kirn, V. S. Kirsebom, O. Kitouni, S. Klaver, K. Klimaszewski, S. Koliiev, A. Kondybayeva, A. Konoplyannikov, P. Kopciewicz, R. Kopecná, P. Koppenburg, M. Korolev, I. Kostiuk, O. Kot, S. Kotriakhova, P. Kravchenko, L. Kravchuk, R. Krawczyk, M. Kreps, F. Kress, S. Kretzschmar, P. Krokovny, W. Krupa, W. Krzemień, W. Kucewicz, M. Kucharczyk, V. Kudryavtsev, H. Kuindersma, G. Kunde, T. Kvaratskheliya, D. Lacarrere, G. Lafferty, A. Lai, A. Lampis, D. Lancierini, J. J. Lane, R. Lane, G. Lanfranchi, C. Langenbruch, J. Langer, O. Lantwin, T. Latham, F. Lazzari, R. Le Gac, S. Lee, R. Lefèvre, A. Leflat, S. Legotin, O. Leroy, T. Lesiak, B. Leverington, H. Li, L. Li, P. Li, Y. Li, Z. Li, X. Liang, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, G. Liu, H. Liu, S. Liu, X. Liu, A. Loi, J. L. Castro, I. Longstaff, J. Lopes, G. Loustau, G. Lovell, Y. Lu, D. Lucchesi, S. Luchuk, M. Martinez, V. Lukashenko, Y. Luo, A. Lupato +499 moresemanticscholar +1 more sourceDual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix +13 morewiley +1 more sourcePerspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman +13 morewiley +1 more source
