Results 71 to 80 of about 15,754,334 (318)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

On a factorization result of \c{S}tef\u{a}nescu

open access: yes, 2021
In this article, some factorization properties of polynomials over discrete valuation domains are elucidated. These properties along with the notion of Newton index of a polynomial leads to a generalization of the main result proved by \c{S}tef\u{a}nescu [`On the factorization of polynomials over discrete valuation domains', \emph{Versita} \textbf{22 ...
Kumar, Sanjeev, Singh, Jitender
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

AXISYMMETRIC BENDING OF CIRCULAR SANDWICH PLATE ON ELASTIC FOUNDATION WITH COMPLICATED STRUCTURE

open access: yesAdvanced Engineering Research, 2014
T h e a p p r o xim a t e clo s e d - fo r m s olu tio n t o t h e p r o ble m o n a cir c ula r m ultila y e r ( s a n d wic h ) c o n s t a n t -t hic k n e s s pla t e b e n din g o n a n ela s tic fo u n d a tio n wit h a c o m plic a t e d s tr u c ...
Sergey Mikhaylovich Ayzikovich   +2 more
doaj   +1 more source

Connected component of positive solutions for one-dimensional p-Laplacian problem with a singular weight

open access: yesOpen Mathematics, 2023
In this article, we prove the existence of eigenvalues for the problem (ϕp(u′(t)))′+λh(t)ϕp(u(t))=0,t∈(0,1),Au(0)−A′u′(0)=0,Bu(1)+B′u′(1)=0\left\{\begin{array}{l}\left({\phi }_{p}\left(u^{\prime} \left(t)))^{\prime} +\lambda h\left(t){\phi }_{p}\left(u ...
Wei Liping, Su Shunchang
doaj   +1 more source

S t a r b u c k s C a f é De lugares, interacciones y prácticas / S t a r b u c k s Coffee - In places, interactions and practices

open access: yesRevista de Direito da Cidade, 2013
DOI: http://dx.doi.org/10.12957/rdc.2013.9956 Trabalho recebido e avaliado pelos Conselhos Editorial e Executivo da Revista de Direito da Cidade Resumen: Un cafe es tambien un refugio. Un lugar que acoge. Una zona de aislamiento donde se dan cita sus parroquianos. Es tambien un espacio laboral, es decir, un sitio en el cual convergen un conjunto de
openaire   +3 more sources

On Exponential Sums, Nowton identities and Dickson Polynomials over Finite Fields [PDF]

open access: yes, 2010
Let $\mathbb{F}_{q}$ be a finite field, $\mathbb{F}_{q^s}$ be an extension of $\mathbb{F}_q$, let $f(x)\in \mathbb{F}_q[x]$ be a polynomial of degree $n$ with $\gcd(n,q)=1$.
Cao, Xiwang, Hu, Lei
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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