Results 51 to 60 of about 14,596,348 (252)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Boundary Value Problems, 2022 In this paper, we consider the small-convection limit of chemotaxis-Navier–Stokes system with logarithmic sensitivity and logistic-type source { n t κ + u κ ⋅ ∇ n κ = Δ n κ − χ ∇ ⋅ ( n κ ∇ log c κ ) + f ( n κ ) , x ∈ Ω , t > 0 , c t κ + u κ ⋅ ∇ c κ = Δ c
Jie Wu
doaj +1 more source
Implementing Inverse Seesaw Mechanism in S U(3) c ⊗S U(4) L ⊗U(1) X Gauge Models [PDF]
International Journal of Theoretical Physics, 2016 Generating appropriate tiny neutrino masses via inverse seesaw mechanism within the framework of a particular S U(3) c ⊗S U(4) L ⊗U(1) X gauge model is the main outcome of this letter.
openaire +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Boundary Value Problems, 2020 In this paper, we study the following fractional Schrödinger equation with electromagnetic fields and critical or supercritical nonlinearity: ( − Δ ) A s u + V ( x ) u = f ( x , | u | 2 ) u + λ | u | p − 2 u , x ∈ R N , $$ (-\Delta )_{A}^{s}u+V(x)u=f ...
Quanqing Li +3 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
GelsBiocompatible nanocomposite hydrogels are emerging as versatile platforms in nanomedicine, particularly when natural proteins are used as both structural and chemical components.
Carmen Salto-Giron +7 more
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Open-charm tetraquark $$X_c$$ X c and open-bottom tetraquark $$X_b$$ X b
European Physical Journal C: Particles and Fields, 2020 Motivated by the LHCb observation of exotic states $$X_{0,1}(2900)$$ X 0 , 1 ( 2900 ) with four open quark flavors in the $$D^- K^+$$ D - K + invariant mass distribution in the decay channel $$B^\pm \rightarrow D^+ D^- K^\pm $$ B ± → D + D - K ± , we ...
Xiao-Gang He, Wei Wang, Ruilin Zhu
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source