Results 71 to 80 of about 14,596,348 (252)

On a factorization result of \c{S}tef\u{a}nescu

open access: yes, 2021
In this article, some factorization properties of polynomials over discrete valuation domains are elucidated. These properties along with the notion of Newton index of a polynomial leads to a generalization of the main result proved by \c{S}tef\u{a}nescu [`On the factorization of polynomials over discrete valuation domains', \emph{Versita} \textbf{22 ...
Kumar, Sanjeev, Singh, Jitender
openaire   +1 more source

A general description of Loran-C: Present and potential applications [PDF]

open access: yes
Loran-C is a low frequency (100 kHz) pulse navigation system. The pulse format and phase stability of the system are of paramount importance for both navigation and time synchronization using this system.
Doherty, R. H.
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

DP093 | HYPOMETHYLATING AGENTS ALONE OR IN COMBINATION WITH VENETOCLAX IN VERY ELDERLY ACUTE MYELOID LEUKEMIA PATIENTS: IS LESS BETTER THAN MORE?

open access: yesHaematologica
Azacitidine/venetoclax combination is the standard of care for acute myeloid leukemia (AML) patients deemed unfit for intensive care programs, according to the VIALE-A trial results.
F. Tarantini   +22 more
doaj  

Estratigrafía del Pleistoceno superior-Holoceno en el área de la laguna costera de Balandra, Estado de Baja California Sur

open access: yesRevista Mexicana de Ciencias Geológicas, 2019
En el piso de la laguna costera de Balandra y en los afloramientos de rocas marinas de los alrededores de la misma, se hizo el estudio de las unidades estratigráficas sedimentarias.
Sergio Pedrín-Avilés   +4 more
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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