Results 41 to 50 of about 14,596,348 (252)
, 2012 In this paper we study the existence of minimizers for $$ F(u) = \1/2\int_{\R^3} |\nabla u|^2 dx + 1/4\int_{\R^3}\int_{\R^3}\frac{| u(x) |^2| u(y) |^2}{| x-y |}dxdy-\frac{1}{p}\int_{\R^3}| u |^p dx$$ on the constraint $$S(c) = \{u \in H^1(\R^3) : \int_ ...
Jeanjean, Louis, Luo, Tingjian
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Boundary Value Problems, 2017 This article deals with integral boundary value problems of the second-order differential equations { u ″ ( t ) + a ( t ) u ′ ( t ) + b ( t ) u ( t ) + f ( t , u ( t ) ) = 0 , t ∈ J + , u ( 0 ) = ∫ 0 1 g ( s ) u ( s ) d s , u ( 1 ) = ∫ 0 1 h ( s ) u ( s )
Qiuyan Zhong, Xingqiu Zhang
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Journal of High Energy Physics, 2018 We describe a class of three Higgs doublet models (3HDMs) with a softly broken U(1) × U(1) family symmetry that enforces a Cabibbo-like quark mixing while forbidding tree-level flavour changing neutral currents. The hierarchy in the observed quark masses
José Eliel Camargo-Molina +3 more
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Peller's problem concerning Koplienko-Neidhardt trace formulae: the unitary case
, 2015 We prove the existence of a complex valued $C^2$-function on the unit circle, a unitary operator U and a self-adjoint operator Z in the Hilbert-Schmidt class $S^2$, such that the perturbated operator $$ f(e^{iZ}U)-f(U) -\frac{d}{dt}\bigl(f(e^{itZ}U)\bigr)
Coine, Clément +4 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Forestist, 1987 The visual quality of an environm ent and, especially, the visitors’ im age of that quality are extrem ely im portant because tlıey a ffect selection, developm ent and popularity of a tourism and recreation area.
Sadık ARTUNÇ
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Boundedness of the extremal solutions in dimension 4 [PDF]
, 2012 In this paper we establish the boundedness of the extremal solution u^* in dimension N=4 of the semilinear elliptic equation $-\Delta u=\lambda f(u)$, in a general smooth bounded domain Omega of R^N, with Dirichlet data $u|_{\partial \Omega}=0$, where f ...
Villegas, Salvador
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