Results 121 to 130 of about 3,775 (171)

Case Report: Diagnostic challenges in VEXAS syndrome with novel ultrastructural lung findings: IgG4-RD and vasculitis as relevant differential diagnoses. [PDF]

Front Immunol
Etzel P, Lang D, Öberseder G, Lamprecht B.   +3 more
europepmc   +1 more source

Primary CD34⁺ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243. [PDF]

Br J Haematol
Nowak D, Demmerle M, Klär A, Streuer A, Riabov V, Altrock E, Rapp F, Belzer AC, Klink T, Hahn M, Hofmann F, Nowak V, Weimer N, Obländer J, Palme I, Göl M, Darwich A, Steiner L, Abba M, Metzgeroth G, Hofmann WK, Schmitt N.   +21 more
europepmc   +1 more source

UBA1-depleted neutrophils disrupt immune homeostasis and induce VEXAS-like autoinflammatory disease in mice. [PDF]

J Clin Invest
Dong G, Liu J, Jin W, Zhou H, Wen Y, Wang Z, Xia K, Zhang J, Ma L, Ma Y, Cai LC, Zhou Q, Wang H, Wei W, Fu Y, Cai Z.   +15 more
europepmc   +1 more source

Expanding the Clinical Spectrum of VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome: The First Report of Histologically Confirmed Neutrophilic Colitis With Rare Muscular and Pancreatic Involvement. [PDF]

Cureus
El Tahech S, Nassereddine H, Moukheiber S, Maalouly G.   +3 more
europepmc   +1 more source

SF3B1-mutant models of RNA mis-splicing uncover UBA1 as a therapeutic target in myelodysplastic neoplasms. [PDF]

Leukemia
Thier J, Hofmann S, Kirchhof KM, Todisco G, Mortera-Blanco T, Lilienthal I, Kanellis DC, Barbosa I, Björklund AC, Deslauriers AG, Bartek J, Herold N, Papaemmanuil E, Papapetrou EP, Hellström-Lindberg E, Moura PL, Lundin V.   +16 more
europepmc   +1 more source

[VEXAS syndrome mimicking relapsing polychondritis: A case report]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Dong Q, He J, Jia Y, Yao H, Zhang X.
europepmc   +1 more source

Exploring glucocorticoid dose-response patterns in VEXAS syndrome: a pilot retrospective study. [PDF]

Rheumatol Int
Giachetti N, Hadjadj J, Gaudré N, Lavigne C, Lacombe V.   +4 more
europepmc   +1 more source

Clinical Manifestations of VEXAS Syndrome Across a Broad Spectrum of UBA1 Mutation Burden. [PDF]

Arthritis Rheumatol
Anderson M, Ercelen D, Richardson A, Kim J, Torene RI, Sirenko M, Haley JS, Cook A, Hill W, Dove J, Retterer K, Carroll E, Carey DJ, Asgari S, Stewart DR, Beck DB.   +15 more
europepmc   +1 more source