Results 151 to 160 of about 4,126 (198)

SOMATIC UBA1 MUTATIONS IN PEDIATRIC MDS/AML: FIRST CASES SUGGEST DISTINCT PATHOGENESIS FROM ADULT VEXAS SYNDROME

Lili Kotmayer, Ninad Oak, Michael Halyko, Rajat Sharma, Sinisa Savic, Fernanda Gutierrez-Rodrigues, Bhavisha A. Patel, David B. Beck, Raul C Ribeiro, Kim E. Nichols, Geoff Shenton, Anjali Sharathkumar, Marcin W Wlodarski   +12 more
openalex   +1 more source

Prevalence and outcome of VEXAS syndrome in unrelated hematopoietic cell transplantation for bone marrow failure. [PDF]

Clin Exp Med
Zaimoku Y, Imi T, Hatada T, Mizumaki H, Mura H, Yoshino H, Kano Y, Kobayashi M, Morishita E, Fushida N, Matsushita T, Mizuguchi K, Ikeda H, Nannya Y, Ogawa S, Hosomichi K, Doki N, Katayama Y, Koike T, Matsuoka KI, Nishida T, Takahashi Y, Kataoka K, Nakazawa H, Ueda Y, Fukuda T, Ichinohe T, Ishimaru F, Onizuka M, Atsuta Y, Miyamoto T, Japanese Society of Transplantation and Cellular Therapy.   +31 more
europepmc   +1 more source

Primary CD34⁺ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243. [PDF]

Br J Haematol
Nowak D, Demmerle M, Klär A, Streuer A, Riabov V, Altrock E, Rapp F, Belzer AC, Klink T, Hahn M, Hofmann F, Nowak V, Weimer N, Obländer J, Palme I, Göl M, Darwich A, Steiner L, Abba M, Metzgeroth G, Hofmann WK, Schmitt N.   +21 more
europepmc   +1 more source

Rapid clinical deployment of UBA1 testing in patients with VEXAS syndrome. [PDF]

Am J Clin Pathol
Wadsworth PA, Chen SB, Lawrence L, Ho CC, Le JE, Libiran P, Grayson PC, Ferrada MA, Beck DB, Suarez CJ.   +9 more
europepmc   +1 more source

Cryo-EM structures of UBA6 reveal mechanisms of E1-E2 specificity and dual FAT10/ubiquitin thioester transfer. [PDF]

Nat Commun
Nayak D, Jia L, Dos Santos Bury P, Ruben EA, Shukla A, Nayak A, Stratton CM, Ebadi P, Cho H, Tumanova AA, Varughese JT, Yuan L, Gao F, Cano KE, Davies C, Sung P, Gack MU, Wasmuth EV, Olsen SK.   +18 more
europepmc   +1 more source

VEXAS syndrome: more than just vacuoles. [PDF]

Hematol Transfus Cell Ther
Barros Pinto MP.
europepmc   +1 more source

A Noval XNA-Based Luminex Assay to Detect UBA1 Somatic Mutations Associated with VEXAS Syndrome

Yunqing Ma, ShianPin Hu, Rui Ni, Wei Liu, Andrew Y. Fu, Michael Y. Sha, Aiguo Zhang, Chuanyi M. Lu   +7 more
openalex   +1 more source

Unravelling the Puzzle: Highlighting a Case of VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Mimicker Presented With Inflammatory Symptoms and Pancytopenia. [PDF]

Cureus
Singh A, Yadav A, Singh A.
europepmc   +1 more source

Monitoring Variant Allele Fraction in VEXAS Syndrome: A Comparison of Digital PCR and Next-Generation Sequencing. [PDF]

EJHaem
Exposito-Bey A, Montes-Cano MA, Payán-Pernía S, García-Lozano JR, González-Escribano MF.   +4 more
europepmc   +1 more source

A cross-sectional survey on VEXAS syndrome: insights from a global expert panel. [PDF]

Clin Rheumatol
Ali SB, Gurnari C.
europepmc   +1 more source