Results 1 to 10 of about 161,044 (231)
The Autoinflammatory Diseases Alliance Registry of monogenic autoinflammatory diseases [PDF]
Frontiers in Medicine, 2022 ObjectiveThe present manuscript aims to describe an international, electronic-based, user-friendly and interoperable patient registry for monogenic autoinflammatory diseases (mAIDs), developed in the contest of the Autoinflammatory Diseases Alliance ...
Carla Gaggiano +103 more
doaj +19 more sources
Interleukin-6 inhibition in the treatment of autoinflammatory diseases [PDF]
Frontiers in Immunology, 2022 Autoinflammatory diseases are characterized by abnormalities that prevent innate immune cells from producing autoantibodies. While interleukin (IL)-6 is not directly associated with inflammasomes, like IL-1β or IL-18, it plays an important role in the ...
Tomohiro Koga +2 more
doaj +4 more sources
Swiss Medical Weekly, 2012 The monogenic autoinflammatory syndromes are conditions caused by mutations of genes coding for proteins that play a pivotal role in the regulation of the inflammatory response. Due to their genetic nature, most of these disorders have an
Silvia Federici +2 more
doaj +6 more sources
Autoinflammatory diseases: what’s behind them and what’s new. A review [PDF]
Dermatology Reports, 2022 Autoinflammatory diseases are characterized by bouts of systemic or localized inflammation in the absence of an infection. While some autoinflammatory diseases are caused by a single gene mutation, others have been shown to be multifactorial, involving ...
Michele Maalouly +2 more
doaj +4 more sources
Dermatologic and Dermatopathologic Features of Monogenic Autoinflammatory Diseases [PDF]
Frontiers in Immunology, 2019 Autoinflammatory diseases include disorders with a monogenic cause and also complex conditions associated to polygenic or multifactorial factors. An increased number of both monogenic and polygenic autoinflammatory conditions have been identified during ...
Ignasi Figueras-Nart +3 more
doaj +4 more sources
Update on ocular manifestations of the main monogenic and polygenic autoinflammatory diseases [PDF]
Frontiers in OphthalmologyAutoinflammatory diseases include disorders with a genetic cause and also complex syndromes associated to polygenic or multifactorial factors. Eye involvement is present in many of them, with different extent and severity.
Alex Fonollosa +12 more
doaj +4 more sources
Autoinflammatory Bone Diseases
Balkan Medical JournalAutoinflammatory bone diseases (AIBDs) constitute a recently identified subset of autoinflammatory diseases. These conditions are characterized by an exaggerated inflammatory response in the bones without any apparent etiology.
Fatih Haşlak +6 more
doaj +5 more sources
Rare Autoinflammatory Diseases
Turkish Archives of Pediatrics, 2021 Systemic autoinflammatory diseases are disorders caused by dysregulation of the innate immune system leading to systemic inflammation. Since the first gene had been identified causing Familial Mediterranean Fever, the most common hereditary systemic autoinflammatory disease, advances in genomic techniques and awareness of the diseases have led to ...
Başaran, Özge +2 more
openaire +3 more sources
Elucidation of the Pathogenesis of Autoinflammatory Diseases Using iPS Cells
Children, 2021 Autoinflammatory diseases are a disease entity caused by the dysregulation of innate immune cells. Typical autoinflammatory diseases are monogenic disorders and often very rare.
Megumu K. Saito
doaj +2 more sources
Orvosi hetilap, 2018 This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms ...
Rigante D., Vitale A., Cantarini L.
core +9 more sources