Results 11 to 20 of about 161,044 (231)

Autoinflammatory Diseases in Childhood

Balkan Medical Journal, 2020
Autoinflammatory diseases are characterized by recurrent fevers and clinical findings of impaired natural immunity and can involve various organ systems. The concept of autoinflammatory disease emerged after the definition of familial Mediterranean fever
Mehmet Yıldız, Fatih Haşlak, Amra Adrovic, Kenan Barut, Özgür Kasapçopur   +4 more
doaj   +2 more sources

Autoinflammatory diseases and the kidney. [PDF]

Immunol Res, 2023
AbstractThe kidney represents an important target of systemic inflammation. Its involvement in monogenic and multifactorial autoinflammatory diseases (AIDs) vary from peculiar and relatively frequent manifestations to some rare but severe features that may end up requiring transplantation.
Hegazy MT, Fayed A, Nuzzolese R, Sota J, Ragab G.   +4 more
europepmc   +5 more sources

Autoinflammatory Bone Diseases [PDF]

Rheumatic Disease Clinics of North America, 2013
Autoinflammatory bone disease is a new branch of autoinflammatory diseases caused by seemingly unprovoked activation of the innate immune system leading to an osseous inflammatory process. The inflammatory bone lesions in these disorders are characterized by chronic inflammation that is typically culture negative with no demonstrable organism on ...
Polly J Ferguson
exaly   +3 more sources

Recommendations for the management of autoinflammatory diseases [PDF]

Annals of the Rheumatic Diseases, 2015
: Autoinflammatory diseases are characterised by fever and systemic inflammation, with potentially serious complications. Owing to the rarity of these diseases, evidence-based guidelines are lacking. In 2012, the European project Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) was launched to optimise and disseminate regimens ...
Ter Haar, Nienke M, Oswald, Marlen, Jeyaratnam, Jerold, Anton, Jordi, Barron, Karyl S, Brogan, Paul A, CANTARINI, LUCA, Galeotti, Caroline, Grateau, Gilles, Hentgen, Veronique, Hofer, Michael, Kallinich, Tilmann, Kone Paut, Isabelle, Lachmann, Helen J, Ozdogan, Huri, Ozen, Seza, Russo, Ricardo, Simon, Anna, Uziel, Yosef, Wouters, Carine, Feldman, Brian M, Vastert, Sebastiaan J, Wulffraat, Nico M, Benseler, Susanne M, Frenkel, Joost, Gattorno, Marco, Kuemmerle Deschner, Jasmin B.   +26 more
core   +16 more sources

Toward an Inclusive, Congruent, and Precise Definition of Autoinflammatory Diseases [PDF]

Frontiers in Immunology, 2017
Autoinflammatory disease was introduced as a concept in 1999, demarcating an entirely new group of diseases in clinical, immunological, and conceptual terms.
Per Wekell, Per Wekell, Stefan Berg, Stefan Berg, Anna Karlsson, Anders Fasth, Anders Fasth   +6 more
doaj   +3 more sources

Autoinflammatory diseases: Emerging phenotypes

Indian Journal of Rheumatology, 2020
Autoinflammatory diseases (AIDs) are a heterogeneous group of genetically inherited disorders involving genes regulating innate immune response. The genetic basis of several AIDs has been characterized and many new syndromes have been identified in the ...
Gummadi Anjani, Surjit Singh, Amit Rawat
doaj   +2 more sources

Systemic autoinflammatory diseases

Journal of Autoimmunity, 2020
Systemic autoinflammatory diseases (SAIDs) are a growing group of disorders caused by a dysregulation of the innate immune system leading to episodes of systemic inflammation. In 1997, MEFV was the first gene identified as disease causing for Familial Mediterranean Fever, the most common hereditary SAID.
Julie Krainer, Andreas Weinhaeusel
exaly   +3 more sources

γδ T Cells in Autoinflammatory Diseases [PDF]

Cells
Autoinflammatory diseases are characterized by inappropriate activation of innate immunity resulting in excessive or persistent inflammation in the absence of infection.
Ilan Bank
doaj   +2 more sources

Vasculitis in Systemic Autoinflammatory Diseases [PDF]

Frontiers in Pediatrics, 2018
Autoinflammatory diseases (AID) are diseases of the innate immune system, characterized by recurrent episodes of localized or systemic inflammation. Vasculitis may accompany AID.
Selcan Demir, Erdal Sag, Fatma Dedeoglu, Seza Ozen   +3 more
doaj   +2 more sources

Autoinflammatory diseases and cardiovascular manifestations

Annals of Medicine, 2011
A host of clinical scenarios can be depicted in hereditary autoinflammatory diseases, and the cardiovascular system can also be involved especially in familial Mediterranean fever (FMF), caused by mutations in the MEFV gene, and tumour necrosis factor ...
Donato Rigante, Luca Cantarini, Massimo Imazio   +2 more
exaly   +2 more sources