Results 11 to 20 of about 2,283,992 (229)
Rare Autoinflammatory Diseases
Turkish Archives of Pediatrics, 2021 Systemic autoinflammatory diseases are disorders caused by dysregulation of the innate immune system leading to systemic inflammation. Since the first gene had been identified causing Familial Mediterranean Fever, the most common hereditary systemic autoinflammatory disease, advances in genomic techniques and awareness of the diseases have led to ...
BAŞARAN, HALİDE ÖZGE +2 more
openaire +4 more sources
Elucidation of the Pathogenesis of Autoinflammatory Diseases Using iPS Cells
Children, 2021 Autoinflammatory diseases are a disease entity caused by the dysregulation of innate immune cells. Typical autoinflammatory diseases are monogenic disorders and often very rare.
Megumu K. Saito
doaj +2 more sources
Orvosi hetilap, 2018 This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms ...
Rigante D., Vitale A., Cantarini L.
core +9 more sources
Autoinflammatory Diseases in Childhood
Balkan Medical Journal, 2020 Autoinflammatory diseases are characterized by recurrent fevers and clinical findings of impaired natural immunity and can involve various organ systems. The concept of autoinflammatory disease emerged after the definition of familial Mediterranean fever
Mehmet Yıldız +4 more
doaj +2 more sources
Autoinflammatory diseases: what’s behind them and what’s new. A review [PDF]
Dermatology Reports, 2022 Autoinflammatory diseases are characterized by bouts of systemic or localized inflammation in the absence of an infection. While some autoinflammatory diseases are caused by a single gene mutation, others have been shown to be multifactorial, involving ...
Michele Maalouly +2 more
doaj +2 more sources
Autoinflammatory diseases: Emerging phenotypes
Indian Journal of Rheumatology, 2020 Autoinflammatory diseases (AIDs) are a heterogeneous group of genetically inherited disorders involving genes regulating innate immune response. The genetic basis of several AIDs has been characterized and many new syndromes have been identified in the ...
Gummadi Anjani, Surjit Singh, Amit Rawat
doaj +2 more sources
Interleukin-6 inhibition in the treatment of autoinflammatory diseases [PDF]
Frontiers in Immunology, 2022 Autoinflammatory diseases are characterized by abnormalities that prevent innate immune cells from producing autoantibodies. While interleukin (IL)-6 is not directly associated with inflammasomes, like IL-1β or IL-18, it plays an important role in the ...
Tomohiro Koga +2 more
doaj +2 more sources
Toward an Inclusive, Congruent, and Precise Definition of Autoinflammatory Diseases [PDF]
Frontiers in Immunology, 2017 Autoinflammatory disease was introduced as a concept in 1999, demarcating an entirely new group of diseases in clinical, immunological, and conceptual terms.
Per Wekell +6 more
doaj +3 more sources
Dermatologic and Dermatopathologic Features of Monogenic Autoinflammatory Diseases [PDF]
Frontiers in Immunology, 2019 Autoinflammatory diseases include disorders with a monogenic cause and also complex conditions associated to polygenic or multifactorial factors. An increased number of both monogenic and polygenic autoinflammatory conditions have been identified during ...
Ignasi Figueras-Nart +3 more
doaj +2 more sources
Vasculitis in Systemic Autoinflammatory Diseases [PDF]
Frontiers in Pediatrics, 2018 Autoinflammatory diseases (AID) are diseases of the innate immune system, characterized by recurrent episodes of localized or systemic inflammation. Vasculitis may accompany AID.
Selcan Demir +3 more
doaj +2 more sources