Results 41 to 50 of about 2,283,992 (229)

Autoinflammatory diseases in Pediatrics

open access: yesArchivos Argentinos de Pediatria, 2013
Monogenic autoinflammatory syndromes are caused by mutations in protein-coding genes that have a pivotal role in the regulation of the inflammatory response. Due to their genetic nature, most of these syndromes usually begin during childhood. They are clinically characterized by recurrent episodes of systemic inflammation (fever with different clinical
Silvia M, Meiorin   +2 more
openaire   +4 more sources

The Interactions Between Autoinflammation and Type 2 Immunity: From Mechanistic Studies to Epidemiologic Associations

open access: yesFrontiers in Immunology, 2022
Autoinflammatory diseases are a group of clinical syndromes characterized by constitutive overactivation of innate immune pathways. This results in increased production of or responses to monocyte- and neutrophil-derived cytokines such as interleukin-1β (
McKella Sylvester   +2 more
doaj   +1 more source

Induced Pluripotent Stem Cell-Derived Monocytes/Macrophages in Autoinflammatory Diseases

open access: yesFrontiers in Immunology, 2022
The concept of autoinflammation, first proposed in 1999, refers to a seemingly unprovoked episode of sterile inflammation manifesting as unexplained fever, skin rashes, and arthralgia.
Takayuki Tanaka   +8 more
doaj   +1 more source

Autoinflammatiós kórképek = Autoinflammatory diseases [PDF]

open access: yes, 2018
Absztrakt: Az autoinflammatiós szindrómák a veleszületett immunrendszert érintő, visszatérő szisztémás gyulladásos tünetekkel, súlyos szövődményekkel jellemezhető kórképek.
Mosdósi, Bernadett   +3 more
core   +1 more source

Cutaneous manifestations of autoinflammatory diseases [PDF]

open access: yesRheumatology and Immunology Research, 2021
Abstract Autoinflammatory diseases (AIDs) are a heterogeneous group of disorders in which recurrent or continuous aseptic inflammation arises primarily through antigen-independent hyperactivation of the innate immune system. The skin is frequently involved with a wide variety of cutaneous manifestations, most of which are non-specific.
Wu, Di, Shen, Min, Yao, Qingping
openaire   +2 more sources

Hereditary systemic autoinflammatory diseases and Schnitzler\u27s syndrome [PDF]

open access: yes, 2021
The systemic autoinflammatory diseases are disorders of the innate immune system distinguished by severe inflammation resulting from dysregulation of the innate immune system.
Savic, Sinisa   +2 more
core   +1 more source

TNF receptor signalling in autoinflammatory diseases [PDF]

open access: yes, 2019
Autoinflammatory syndromes are a group of disorders characterised by recurring episodes of inflammation as a result of specific defects in the innate immune system.
Lara-Reyna, Samuel; id_orcid   +7 more
core   +1 more source

Prevalence of Allergic Diseases in Patients with Common Autoinflammatory Diseases

open access: yes, 2021
Objective: Autoinflammatory diseases are driven by abnormal activation of the innate immune system. Although allergic diseases are known to be mediated by the T helper 2 response, new mechanisms are put forward about the activation of innate immunity ...
Erdogan, Tuba   +2 more
core   +1 more source

Long-Term Outcomes of Behçet’s Syndrome-Related Uveitis: A Monocentric Italian Experience

open access: yesMediators of Inflammation, 2020
Objectives. To examine demographic and clinical characteristics and long-term visual outcome in a cohort of Italian patients affected by Behçet’s uveitis (BU). Materials and Methods.
Jurgen Sota   +9 more
doaj   +1 more source

Monogenic autoinflammatory diseases in children: single center experience with clinical, genetic, and imaging review

open access: yesInsights into Imaging, 2020
Purpose 1. To review the contemporary literature and present a list of the imaging findings for patients with autoinflammatory diseases from our hospital. All these patients are found to have a genetic mutation that is responsible for their disease.
Alaa N. Alsharief   +6 more
doaj   +1 more source

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