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Familial Mediterranean fever

Rheumatology International, 2005
Familial Mediterranean fever (FMF) is the most frequent hereditary inflammatory disease characterized by self-limited recurrent attacks of fever and serositis. It is transmitted in an autosomal recessive pattern and affects certain ethnic groups mainly Jews, Turks, Arabs, and Armenians. FMF is caused by mutations in MEFV gene, which encodes pyrin. This
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Familial Mediterranean fever

Pediatric Nephrology, 2003
Familial Mediterranean fever (FMF) is the most frequent periodic syndrome characterized by recurrent attacks of polyserositis. Fever, abdominal pain, chest pain, and arthritis/arthralgia are the leading symptoms. It is an autosomal recessive disorder, which primarily affects Jewish, Armenian, Turkish, and Arab populations.
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Familial Mediterranean fever

The Lancet, 1996
Familial Mediterranean fever is an inherited disorder which causes episodes of severe pain and fever lasting a few days and then recurring shortly afterward. Joints, peritoneal and pleural spaces are primarily affected displaying acute inflammation and an influx of neutrophils into the inflamed area. Keywords: colchicine; amyloid; complement;
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Familial Mediterranean fever in Arabs

The Lancet, 2006
Autoinflammatory diseases are a group of disorders characterised by seemingly unprovoked inflammation in the absence of high-titre autoantibodies or antigen-specific T cells, and include the hereditary periodic fever syndromes. Familial Mediterranean fever (FMF) is an archetypal autoinflammatory disorder, which is autosomal recessive and has a high ...
Hatem, El-Shanti   +2 more
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The arthritis of familial mediterranean fever

Seminars in Arthritis and Rheumatism, 1992
Familial Mediterranean fever (FMF) is a disease of unknown etiology and pathogenesis. In addition to fever, arthritis is among its most frequent manifestations. The arthritis of FMF is typically an acute, episodic, self-limited process with no sequelae.
A, Garcia-Gonzalez, M H, Weisman
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Familial Mediterranean fever and microRNAs

International Journal of Immunogenetics, 2023
AbstractFamilial Mediterranean fever (FMF) is an inherited disorder caused by the gain of function mutations in MEFV (MEditerranean FeVer) gene loci. FMF affects more than 100,000 people worldwide and generally seen in the eastern Mediterranean region and causes the lifelong diseases which have a significant effect on the patient's life quality and ...
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Familial Mediterranean Fever Gene

New England Journal of Medicine, 1998
To the Editor: Babior and Matzner (Nov. 20 issue)1 state that the recently identified familial Mediterranean fever (FMF) gene2,3 can be used to establish the diagnosis of this disease.
A H, Holmes, D R, Booth, P N, Hawkins
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Pericarditis in Familial Mediterranean Fever

Archives of Pediatrics & Adolescent Medicine, 1968
FAMILIAL Mediterranean fever (FMF) is an autosomal recessive disorder prevalent among Sephardi Jews, Armenians, and Levantine Arabs. It is characterized by (1) recurrent episodic attacks of fever accompanied by pain in the abdomen, chest, or joints, and (2) early death due to amyloidosis.
U, Raviv, A, Rubinstein, A E, Schonfeld
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Familial Mediterranean fever (FMF) phenotype in patients homozygous to the MEFV M694V mutation.

European Journal of Medical Genetics, 2019
The clinical presentation of familial Mediterranean fever (FMF) is remarkably variable, ranging from a quiescent to a severe and disabling disease. The M694V mutation is one of approximately 300 published genetic variations in the FMF gene.
C. Grossman   +3 more
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Arthritis in familial Mediterranean fever

Rheumatology International, 2001
We studied the rheumatic and various clinical manifestations of familial Mediterranean fever (FMF) in Lebanon. A retrospective review was performed of the medical records of 74 FMF patients seen at the American University of Beirut Medical Centre (AUB-MC) from 1979 to 1996. We also reviewed the medical literature from 1968 to 2000 using MEDLINE and the
I, Uthman   +4 more
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