Results 51 to 60 of about 168,848 (280)

NALP1 in vitiligo-associated multiple autoimmune disease. [PDF]

, 2007
BACKGROUND: Autoimmune and autoinflammatory diseases involve interactions between genetic risk factors and environmental triggers. We searched for a gene on chromosome 17p13 that contributes to a group of epidemiologically associated autoimmune and ...
Bennett, DC, Fain, PR, Gowan, K, Jin, Y, LaBerge, G, Mailloux, CM, Riccardi, SL, Spritz, RA   +7 more
core   +1 more source

Development of the autoinflammatory disease damage index (ADDI) [PDF]

, 2016
OBJECTIVES: Autoinflammatory diseases cause systemic inflammation that can result in damage to multiple organs. A validated instrument is essential to quantify damage in individual patients and to compare disease outcomes in clinical studies.
Al-Mayouf, SM, Amaryan, G, Annink, KV, Anton, J, Barron, KS, Benseler, SM, Brogan, PA, Cantarini, L, Cattalini, M, Cochino, AV, De Benedetti, F, De Jesus, AA, Dedeoglu, F, Della Casa Alberighi, O, Demirkaya, E, Dolezalova, P, Durrant, KL, Fabio, G, Frenkel, J, Gallizzi, R, Gattorno, M, Goldbach-Mansky, R, Hachulla, E, Hentgen, V, Herlin, T, Hofer, M, Hoffman, HM, Insalaco, A, Jansson, AF, Kallinich, T, Koné-Paut, I, Kozlova, A, Kuemmerle-Deschner, JB, Lachmann, HJ, Laxer, RM, Martini, A, Nielsen, S, Nikishina, I, Ombrello, AK, Ozen, S, Papadopoulou-Alataki, E, Quartier, P, Ravelli, A, Rigante, D, Russo, R, Simon, A, Ter Haar, NM, Trachana, M, Uziel, Y   +48 more
core   +2 more sources

Drug Retention Rates and Treatment Discontinuation among Anti-TNF-α Agents in Psoriatic Arthritis and Ankylosing Spondylitis in Clinical Practice

Mediators of Inflammation, 2014
Objective. The study aim was to determine treatment persistence rates and to identify causes of discontinuation in psoriatic arthritis (PsA) and ankylosing spondylitis (AS) patients in clinical practice. Methods.
Marta Fabbroni, Luca Cantarini, Francesco Caso, Luisa Costa, Veronica Anna Pagano, Bruno Frediani, Stefania Manganelli, Mauro Galeazzi   +7 more
doaj   +1 more source

Renal involvement in autoinflammatory diseases

Kidney Diseases, 2023
Background: Autoinflammatory diseases (AIDs) were first proposed 20 years ago and caused by dysregulation of the innate immune system leading to episodes of systemic inflammation.
Changming Zhang, Jiahui Peng, Zhihong Liu, Qing Zhou   +3 more
doaj   +1 more source

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever [PDF]

, 2018
Pyroptosis is an inflammasome-induced lytic cell death mode, the physiological role of which in chronic inflammatory diseases is unknown. Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease worldwide, affecting an ...
Chi, Hongbo, Kambara, Hiroto, Kanneganti, Apurva, Lamkanfi, Mohamed, Luo, Hongbo R, Malireddi, RK Subbarao, Tillman, Heather, Van Gorp, Hanne, Vande Walle, Lieselotte, Viana Saavedra, Pedro Henrique, Vogel, Peter, Xavier, Ramnik J   +11 more
core   +1 more source

Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey. [PDF]

, 2020
Primary Immune Regulatory Disorders (PIRD) are an expanding group of diseases caused by gene defects in several different immune pathways, such as regulatory T cell function.
Allenspach, Eric J, Andolina, Jeffrey R, Aquino, Victor M, Bacchetta, Rosa, Bednarski, Jeffrey J, Bhatia, Monica, Buckley, Rebecca H, Burroughs, Lauri M, Caywood, Emi, Chan, Alice Y, Chandrakasan, Shanmuganathan, Chellapandian, Deepak, Chen, Karin, Chong, Hey, Cooper, Megan A, Cowan, Morton J, Craddock, John A, Cuvelier, Geoffrey DE, Davila Saldana, Blachy J, de la Morena, Maria Teresa, Dorsey, Morna J, Dvorak, Christopher C, Forbes, Lisa R, Gennery, Andrew R, Goldman, Frederick D, Griffith, Linda M, Haddad, Elie, Heimall, Jennifer, Jordan, Michael B, Kapoor, Neena, Kohn, Donald B, Leiding, Jennifer W, Liu, Xuerong, Logan, Brent R, Marsh, Rebecca A, Martinez, Caridad, Meyts, Isabelle, Miller, Holly K, Notarangelo, Luigi D, Oshrine, Benjamin R, Pai, Sung-Yun, Parikh, Suhag, Prockop, Susan E, Puck, Jennifer M, Pulsipher, Michael A, Seidel, Markus G, Seroogy, Christine M, Shenoy, Shalini, Shereck, Evan, Shyr, David C, Skoda-Smith, Suzanne, Slatter, Mary, Smith, Angela R, Sullivan, Kathleen E, Torgerson, Troy R, Uzel, Gulbu, Vander Lugt, Mark T, Walter, Jolan E, Weinacht, Katja G, Wright, Nicola   +59 more
core   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source

Efficacy of combined JAK1/2 inhibition and cyclosporine in paediatric-onset Still’s disease with lung involvement: a case report

Pediatric Rheumatology Online Journal
Background Paediatric-onset Still’s disease is a severe autoinflammatory disorder marked by high fever, systemic inflammation, rash, organomegaly, and arthritis.
Serena Palmeri, Maddalena Lancieri, Jacopo Ferro, Pietro Salvati, Martino Cheli, Riccardo Papa, Silvia Rosina, Stefano Volpi, Valerio Gaetano Vellone, Angelo Ravelli, Marco Gattorno, Roberta Caorsi   +11 more
doaj   +1 more source

Modulation of Autoimmune and Autoinflammatory Diseases by Gasdermins

Frontiers in Immunology, 2022
Autoimmune diseases and autoinflammatory diseases are two types of the immune system disorders. Pyroptosis, a highly inflammatory cell death, plays an important role in diseases of immune system.
Fang Liang, Weixiao Qin, Yilan Zeng, Dan Wang   +3 more
doaj   +1 more source

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1 beta inhibition [PDF]

, 2006
BACKGROUND:Neonatal-onset multisystem inflammatory disease is characterized by fever, urticarial rash, aseptic meningitis, deforming arthropathy, hearing loss, and mental retardation.
Adams, BS, Aksentijevich, I, Beitz, LO, Brewer, C, Butman, JA, Canna, SW, Cole, JL, Dailey, NJ, Fuhlbrigge, RC, Gardner, G, Gelabert, A, Goldbach-Mansky, R, Hannan, WP, Haverkamp, MH, Hawkins, PN, Hill, S, Hoffmann, SC, Holland, SM, Horn, W, Jarvis, JN, Jones, J, Karp, BI, Kastner, DL, Kim, HJ, Moore, TL, O'Neil, K, Paul, SM, Penzak, SR, Pham, TH, Pucino, F, Rubin, BI, Shaham, B, Snyder, C, Stein, L, Turner, ML, Vehe, RK, Warren, RW, Wesley, RA, Wiggs, E, Zalewski, C   +39 more
core