Results 71 to 80 of about 161,044 (231)

PW03-034 - How to classify autoinflammatory diseases?

, 2013
International audienceIntroductionDefinitions and classifications of autoinflammatory diseases have been multiple. Their succession highlightsthe advances in our understanding of the innate immune system, especially the role of interleukin 1b and ...
I Jéru, Hentgen, Véronique, G Grateau, V Hentgen, Steichen, Olivier, S Amselem, Jéru, Isabelle, K Stankovic, Grateau, Gilles, Stojanovic, Katia, Stankovic, Amselem, Serge, O Steichen   +11 more
core   +1 more source

Real-Life Data on the Efficacy of Canakinumab in Patients with Adult-Onset Still’s Disease

Mediators of Inflammation, 2020
Background. Interleukin-1 inhibition has revealed to be a successful treatment approach for patients with adult-onset Still’s disease (AOSD). However, real-life experience is focused on the use of anakinra, while data about canakinumab (CAN) are mainly ...
Antonio Vitale, Virginia Berlengiero, Jurgen Sota, Luisa Ciarcia, Nicola Ricco, Sara Barneschi, Mariam Mourabi, Giuseppe Lopalco, Chiara Marzo, Francesca Bellisai, Florenzo Iannone, Bruno Frediani, Luca Cantarini   +12 more
doaj   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Spectrum of Large- and Medium-Vessel Vasculitis in Adults: Neoplastic, Infectious, Drug-Induced, Autoinflammatory, and Primary Immunodeficiency Diseases [PDF]

, 2022
PURPOSE OF REVIEW: To provide a comprehensive review of drugs and neoplastic, infectious, autoinflammatory, and immunodeficiency diseases causing medium- to large-vessel vasculitis in adults with emphasis on information essential for the initial ...
Recher, Mike, Fabian Lötscher, Pop, Roxana, Seitz, Pascal, Mike Recher, Luca Seitz, Seitz, Luca, Pascal Seitz, Lötscher, Fabian, Roxana Pop   +9 more
core   +1 more source

Clustering reveals diagnostic overlap between Still’s disease and a hyperinflammatory subset of seronegative rheumatoid arthritis

Scientific Reports
Still’s disease (SD) and rheumatoid arthritis (RA), particularly seronegative RA, may overlap clinically and biologically, complicating diagnosis. We explored data-driven overlaps between SD, seronegative RA, and seropositive RA using unsupervised ...
Alexandre Mercier-Guery, Thomas El-Jammal, Nour El-Nayef, Emmanuel Massy, Nicolas Fournier, Pascal Sève, Cyrille Confavreux, Yvan Jamilloux, Fabienne Coury   +8 more
doaj   +1 more source

Case report: Sulfasalazine-induced hypersensitivity

Frontiers in Medicine, 2023
Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is a systemic inflammatory condition that is characterized by multisystemic involvement (liver, blood, and skin), heterogeneous manifestations ...
Ekaterina M. Kuchinskaya, Irina A. Chikova, Mikhail M. Kostik, Mikhail M. Kostik   +3 more
doaj   +1 more source

Interleukin-1, inflammasome and autoinflammatory diseases

, 2018
International audienceInterleukin-1 is a major cytokine of innate immunity and inflammation. It exerts various systemic effects during the inflammatory response, such as fever induction, thrombopoiesis and granulopoiesis, or leukocyte recruitment.
Barba, T., Seve, P., Py, B.F., Broussolle, C., Lefeuvre, L., Bourdonnay, E., Jamilloux, Y., Gerfaud-Valentin, M., Henry, T.   +8 more
core   +1 more source

High‐ and Ultra‐High‐Frequency Ultrasound Identifies a Subclinical Link Between Suppurative Comedonal Nevus and Hidradenitis Suppurativa

Journal of Ultrasound in Medicine, EarlyView.
Suppurative nevus comedonicus (SNC) is a variant of nevus comedonicus in which the characteristic features coexist with recurrent inflammatory lesions that clinically resemble those of hidradenitis suppurativa (HS). We present the ultrasound characteristics of this entity and emphasize the value of high‐resolution dermatologic ultrasound both as a ...
Marta Ivars, Katia Henostroza, Fabià Torres‐Betato, Eva Vilarrasa, Ximena Wortsman   +4 more
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Pyoderma Gangrenosum: A Retrospective Cohort Study of Comorbidities and Therapies in Over 65,000 Patients in the TriNetX Database

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis associated with systemic inflammatory diseases and malignancy. Although biologic therapies demonstrate efficacy in PG, the extent of their real‐world use remains incompletely characterized.
Rhiannon Grange, Tara Sholji, Marra Aghajani, Cindy Kok, John Frew   +4 more
wiley   +1 more source