Results 21 to 30 of about 2,283,992 (229)
Macroglobulinemia and autoinflammatory disease [PDF]
Rheumatology and Immunology Research, 2021 Abstract Macroglobulinemia is associated with Schnitzler syndrome (SchS) and Waldenstrom macroglobulinemia (WM). The aim of this article was to review the above-mentioned two diseases from clinical aspects and their potential genetic links. We performed a PubMed search using the following keywords: “SchS,” “WM,” “autoinflammatory disease,
Navetta-Modrov, Brianne, Yao, Qingping
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An Update on Autoinflammatory Diseases [PDF]
Current Medicinal Chemistry, 2013 Autoinflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells and auto antibodies). Recently, the increased knowledge
Ciccarelli F +2 more
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The Use of Interleukine-1 Inhibitors in Familial Mediterranean Fever Patients: A Narrative Review
Frontiers in Immunology, 2020 Purpose: Familial Mediterranean fever (FMF) is the most common monogenic auto-inflammatory disease characterized by recurrent attacks of fever and serositis.
Véronique Hentgen +3 more
doaj +1 more source
Bridging autoinflammatory and autoimmune diseases
The Egyptian Journal of Internal Medicine, 2021 Background Autoimmunity is used to cause by impairment of adaptive immunity alone, whereas autoinflammatory was originally defined as a consequence of unregulated innate immunity.
Emad M. El-Shebiny +3 more
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Autoinflammatory disease in the lung [PDF]
Immunology, 2018 SummaryAscertaining the dominant cell type driving an immunological disease is essential to understanding the causal pathology and, therefore, selecting or developing an effective treatment. Classifying immunological diseases in this way has led to successful treatment regimens for many monogenic diseases; however, when the dominant cell type is ...
Scambler, T +4 more
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Designation of Autoinflammatory Skin Manifestations With Specific Genetic Backgrounds
Frontiers in Immunology, 2020 “Autoinflammatory disease (AiD)” has first been introduced in 1999 when the responsible gene for the familial Hibernean fever or autosomal dominant-type familial Mediterranean fever-like periodic fever syndrome was reportedly identified as tumor necrosis
Nobuo Kanazawa
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Monogenic autoinflammatory diseases [PDF]
Rheumatology, 2014 During the past 15 years, a growing number of monogenic inflammatory diseases have been described and their respective responsible genes identified. The proteins encoded by these genes are involved in the regulatory pathways of inflammation and are mostly expressed in cells of the innate immune system.
Ricardo A G, Russo, Paul A, Brogan
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Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Paraproteinemia in Autoinflammatory Diseases
, 2022 Autoinflammatory diseases represent clinical entities characterized by recurrent episodes of systemic and organ-specific inflammation determined by the primary deregulation of the innate immune system.
Vitale A., Cantarini L.
core +1 more source
Frontiers in Immunology, 2023 BackgroundHumoral and cellular immune responses are known to be crucial for patients to recover from COVID-19 and to protect them against SARS-CoV-2 reinfection once infected or vaccinated.ObjectivesThis study aimed to investigate humoral and T cell ...
Natalia Egri +9 more
doaj +1 more source