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Ubiquitin Ligases: Structure, Function, and Regulation [PDF]
Ubiquitin E3 ligases control every aspect of eukaryotic biology by promoting protein ubiquitination and degradation. At the end of a three-enzyme cascade, ubiquitin ligases mediate the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to ...
Ning Zheng, Nitzan Shabek
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Structural insights into the catalysis and regulation of E3 ubiquitin ligases
Nature Reviews Molecular Cell Biology, 2016Danny Huang +2 more
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Ubiquitin ligases in oncogenic transformation and cancer therapy
Nature Reviews Cancer, 2017Jianfei Qi, Daniela Senft, Qi Jianfei
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