Results 261 to 270 of about 349,913 (393)

Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP

, 2017
Pradeep Bist, Wan Shoo Cheong, Aylwin Ng, Neha Dikshit, Bae-Hoon Kim, Niyas Kudukkil Pulloor, Hanif Javanmard Khameneh, Matija Hedl, Avinash R. Shenoy, Vanniarajan Balamuralidhar, Najib Bin Abdul Malik, Michelle Hong, Albert Neutzner, Keh-Chuang Chin, Koichi S. Kobayashi, Antonio Bertoletti, Alessandra Mortellaro, Clara Abraham, John D. MacMicking, Ramnik J. Xavier, Bindu Sukumaran   +20 more
openalex   +1 more source

Role of the C‐terminus of Saccharomyces cerevisiae ubiquitin‐conjugating enzyme (Rad6) in substrate and ubiquitin‐protein‐ligase (E3‐R) interactions [PDF]

, 1994
Bilha Raboy, Richard G. Kulka
openalex   +1 more source

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

Advanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao, Yaqin Huang, Jiazhong Shi, Xiaozhou Zhou, Johan Bourghardt Fagman, Liwei Wang, Sha Liu, Wuxing Wang, Yuting Liu, Zhiwen Chen, Jin Yang   +10 more
wiley   +1 more source

The ubiquitin ligase NKLAM promotes apoptosis and suppression of cell growth. [PDF]

J Biol Chem
Willard PA, Kornbluth J.
europepmc   +1 more source

SCF ubiquitin ligase-targeted therapies

Nature reviews. Drug discovery, 2014
Jeffrey R. Skaar, J. Pagan, M. Pagano
semanticscholar   +1 more source

Epidermal Cell Dynamics Regulates Rice Lamina Joint Morphogenesis and Leaf Angle Formation through OsZHD1 and OsZHD2 Regulation

Advanced Science, EarlyView.
The lamina joint determines leaf angle and plant architecture. Xu et al. establish a live‐imaging system for the rice lamina joint and reveal that asymmetric epidermal cell elongation and division between the lateral and medial edges drive leaf angle formation.
Yiru Xu, Heng Zhou, Xiaojiang Wu, Wuyu Cui, Shouling Xu, Xi He, Dan Xiang, Ming Zhou, Xiuqin Rao, Lilan Hong   +9 more
wiley   +1 more source

Deletion of the E3 ubiquitin ligase LRSAM1 fosters intracellular <i>Staphylococcus aureus</i> survival. [PDF]

Front Cell Infect Microbiol
Plöhn O, Singh AK, Greger C, Wolfgramm H, Baglanova M, Surmann K, Völker U, Bröker BM, Becker K, Seifert U, Cammann C.   +10 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

The ubiquitin ligase Triad1 influences myeloid leukemogenesis by regulating the integrated stress response. [PDF]

J Biol Chem
Wang H, Suh F, Fischietti M, Wray B, Filip SK, Faull PA, Hu L, Huang W, Liu B, Platanias LC, Eklund EA.   +10 more
europepmc   +1 more source

Targeted Degradation of Abscisic Acid Receptors Is Mediated by the Ubiquitin Ligase Substrate Adaptor DDA1 in Arabidopsis[W]

The Plant Cell, 2014
M. L. Irigoyen, Elisa Iniesto, Lesia Rodriguez, María Isabel Puga, Y. Yanagawa, E. Pick, E. Strickland, J. Paz-Ares, N. Wei, G. De Jaeger, P. L. Rodriguez, X. Deng, V. Rubio   +12 more
semanticscholar   +1 more source