Results 291 to 300 of about 254,188 (362)

ETV4 promotes ovarian cancer growth by regulating mitochondrial function through Mfn2 ubiquitination mediated by the E3 ubiquitin ligase MARCH9. [PDF]

Cell Biol Toxicol
Wang Y, Wang Z, Chen J, Cai L, Luo X, Wu N.   +5 more
europepmc   +1 more source

A STOP‐Gain RNF213 Variant Causes Chorea, Stroke‐Like Episodes, and Leigh Syndrome‐Like Encephalopathy

Movement Disorders, EarlyView.
Roberta Bovenzi, Mariasavina Severino, Jennifer Nichols, Fred Shen, Ignacio J. Keller Sarmiento, Bernabe I. Bustos, Lisa Kinsley, Dimitri Krainc, Niccolò E. Mencacci   +8 more
wiley   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase. [PDF]

Autophagy
Fiesel FC, Bustillos BA, Watzlawik JO, Chen CXQ, Berryer MH, Zhang J, Boneski PK, Hayes CS, Bredenberg JM, Deneault E, You Z, Abdien N, Aprahamian N, Goldsmith TM, Baninameh Z, Cocker LT, Zhang H, Goldberg MS, Fon EA, Trempe JF, Virdee S, Durcan TM, Springer W.   +22 more
europepmc   +1 more source

Challenges and opportunities for the diverse substrates of SPOP E3 ubiquitin ligase in cancer. [PDF]

Theranostics
Yang X, Zhu J, Tao X, Gao F, Cai Y, Lv Y, Xie S, Xie K, Lan T, Han J, Wu H.   +10 more
europepmc   +1 more source

Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways. [PDF]

J Cell Biol
Dennison DD, Baldridge RD.
europepmc   +1 more source

Ubiquitin E3 ligase MARCH10 targets influenza hemagglutinin for ubiquitination

Cellular Signalling
Tsai, MuChun, Koch, Dan, Forchione, Anna, Farkas, Laszlo, El-Mergawy, Rabab, Londino, James D., Mallampalli, Rama K.   +6 more
openaire   +2 more sources

E3 ubiquitin ligase Listerin regulates macrophage cholesterol efflux and atherosclerosis by targeting ABCA1. [PDF]

J Clin Invest
Cao L, Zhang J, Yu L, Yang W, Qi W, Ren R, Liu Y, Hou Y, Cao Y, Li Q, Wang X, Zhang Z, Li B, Sui W, Zhang Y, Gao C, Zhang C, Zhang M.   +17 more
europepmc   +1 more source

Natural variation of an E3 ubiquitin ligase encoding gene Chalk9 regulates grain chalkiness in rice. [PDF]

Nat Commun
Hu Z, Liu H, Guo M, Han X, Li Y, Chen R, Guo Y, Yang Y, Sun S, Zhou Y, Gu M, Yan C.   +11 more
europepmc   +1 more source

Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2.

J Cell Sci
Narendradev ND, Ravindran R, Jain P, Chaudhary S, Velikkakath AKG, Sudharman A, Janardhanan A, Nag TC, Yadav SC, Srinivasula SM.   +9 more
europepmc   +1 more source